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Interactions of some commonly used drugs with human α-thrombin.
Author: ChittalakkottuSadasivan, NairDivya Gopalakrishnan, NarayananSunilkumar Puthenpurackal
Original Abstract of the Article :
Adverse side effects of drugs are often caused by the interaction of drug molecules to targets other than the intended ones. In this study, we investigated the off-target interactions of some commercially available drugs with human α-thrombin. The drugs used in the study were selected from Super Dru...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1080/07391102.2014.923329
データ提供:米国国立医学図書館(NLM)
The Hidden Interactions of Common Drugs with Human Thrombin
The world of [pharmacology] is a vast and intricate desert, where drug molecules can interact with various targets in unexpected ways. This study explores the off-target interactions of some commonly used drugs with [human α-thrombin], a key protein involved in blood clotting. It's like discovering a hidden oasis in the desert of drug interactions, revealing potential consequences and new therapeutic possibilities.
The authors investigated the interactions of several drugs with [thrombin] using both computational and experimental approaches. They sought to identify drugs that might exhibit off-target effects on [thrombin], potentially leading to unintended consequences or offering new therapeutic opportunities. Their findings highlight the importance of considering the complex interplay between drugs and biological targets, particularly when it comes to blood clotting and other crucial physiological processes.
Unveiling the Hidden Interactions: A New Perspective on Drug Effects
This study reveals the unexpected interactions of some commonly used drugs with [thrombin]. This discovery is like finding a hidden spring in the desert of drug interactions, offering a deeper understanding of the potential effects of medications. This research underscores the importance of considering off-target effects when developing and using medications, potentially leading to safer and more effective therapies.
The Potential for New Therapeutic Applications
This research opens up new avenues for potential therapeutic applications. It's like finding a new pathway through the desert, leading to new opportunities for drug development and treatment strategies. This research highlights the potential for repurposing existing drugs for new indications, as well as developing novel drugs that target specific interactions with [thrombin].
Dr. Camel's Conclusion
This research provides a fascinating glimpse into the complex world of drug interactions, revealing unexpected connections between commonly used drugs and [thrombin]. This discovery is like finding a hidden oasis in the desert of drug research, offering both a cautionary tale and a source of inspiration for future drug development and treatment strategies.
Date :
- Date Completed 2016-01-15
- Date Revised 2020-12-09
Further Info :
Related Literature
English
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