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Oral N-acetylprocainamide compared to quinidine plus digoxin in the chronic suppression of atrial flutter in humans.

Author: FeldG K, NademaneeK, NollE, SinghB N

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, Non-P.H.S.Research funding provided by US government agencies other than the Public Health Service.

Overview

N-acetylprocainamide was more effective and better tolerated than quinidine plus digoxin in suppressing atrial flutter in 18 patients.
Paper Details　
Original Abstract of the Article :
Antiarrhythmic therapy for the suppression of atrial flutter has conventionally entailed the use of a class Ia agent such as quinidine or procainamide. However, atrial flutter often recurs despite the use of these conventional antiarrhythmic regimens. Experimental and clinical evidence suggests that...See full text at original site
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引用元：
https://doi.org/10.1007/BF01883864

データ提供：米国国立医学図書館（NLM）

A New Approach to Atrial Flutter

Hello, fellow researchers, Dr. Camel here. Today, I'm excited to journey into the fascinating world of atrial flutter, a common heart rhythm disorder. This research explores a promising new approach to managing atrial flutter, comparing the efficacy of N-acetylprocainamide (a class III antiarrhythmic agent) to the conventional regimen of quinidine and digoxin. It's like navigating a desert landscape, searching for the most effective path to restore heart rhythm stability.

N-Acetylprocainamide: A Promising Alternative

The study reveals that N-acetylprocainamide may be more effective and better tolerated than the conventional regimen of quinidine plus digoxin for suppressing atrial flutter. It's like discovering a new oasis, offering a more effective and gentler approach to managing this heart rhythm disorder. The research highlights the importance of exploring alternative treatments for atrial flutter, particularly those that offer improved efficacy and tolerability.

A Step Towards Better Heart Health

The findings of this study suggest that N-acetylprocainamide could be a valuable addition to the treatment options for atrial flutter. It's a hopeful sign in the desert of heart disease research, offering a potential pathway to improved heart health. Further research is needed to confirm these findings and explore the long-term safety and efficacy of this promising new agent.

Dr. Camel's Conclusion

This research underscores the importance of seeking innovative solutions in the field of cardiology. It highlights the potential of N-acetylprocainamide as a promising alternative to conventional treatments for atrial flutter, offering a path towards improved heart health and well-being. It's a journey through the desert of medical research, where we continuously strive to discover new oases of hope and better treatment options for patients.

Date :
  1. Date Completed 1991-03-28
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

2484856

DOI: Digital Object Identifier

10.1007/BF01883864

Related Literature

Article Analysis
・Side Effects of procainamide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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