An investigator-initiated, double-blind, vehicle-controlled pilot study: assessment for tachyphylaxis to topically occluded halobetasol 0.05% ointment in the treatment of psoriasis.

Author: CzarnowickiTali, IngberArie, LebwohlMark, LinknerRita V, Suárez-FariñasMayte

Paper Details 
Original Abstract of the Article :
BACKGROUND: Topical corticosteroids are the most common first-line treatment for psoriasis. Tachyphylaxis, a decreased response to treatment with repetitive application of the drug, is a controversial phenomenon associated with topical corticosteroid treatment. OBJECTIVE: We sought to prove or disp...See full text at original site
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引用元:
https://doi.org/10.1016/j.jaad.2014.05.040

データ提供:米国国立医学図書館(NLM)

Tachyphylaxis to Topical Corticosteroids: A Desert of Uncertainties

Imagine you're a traveler in the desert, relying on a precious water source to stay hydrated. But what if the water source starts to dry up? That's kind of like what happens with tachyphylaxis, a phenomenon where topical corticosteroids become less effective over time. This study is like a scientific expedition, seeking to unravel the mysteries of tachyphylaxis.

The researchers conducted a pilot study to see if there was evidence of tachyphylaxis to halobetasol, a common topical corticosteroid used to treat psoriasis. They found that there was no evidence of tachyphylaxis, which is like finding a consistent water source in the desert, providing relief to those who need it. However, the study was relatively small, so more research is needed to confirm these findings.

Topical Corticosteroids: Finding the Right Oasis in Psoriasis Treatment

This study offers hope for patients with psoriasis who rely on topical corticosteroids for treatment. The findings suggest that tachyphylaxis may not be as common as previously thought, which is like discovering a new oasis in the desert of psoriasis treatment.

Navigating the Desert of Psoriasis

Psoriasis is a chronic skin condition that can be challenging to manage. It's like a long journey through a desert, with ups and downs along the way. This study provides valuable insights into the effectiveness of topical corticosteroids, helping patients and healthcare providers find the right treatments and strategies for managing psoriasis.

Dr.Camel's Conclusion

This study is a reminder that even in the seemingly barren desert of psoriasis research, there are still new discoveries to be made. The findings suggest that topical corticosteroids might be a more reliable treatment option than previously thought, offering hope for patients seeking relief. Remember, the desert is full of surprises, and with perseverance, we can find new ways to manage psoriasis and improve the lives of those affected by this condition.
Date :
  1. Date Completed 2015-01-21
  2. Date Revised 2014-12-02
Further Info :

Pubmed ID

24929883

DOI: Digital Object Identifier

10.1016/j.jaad.2014.05.040

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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