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Phase II evaluation of peroral carmofur, cyclophosphamide, and hexamethylmelamine as a second-line therapy in advanced epithelial ovarian carcinoma.
Author: GröhnP, HeinonenE, KivinenS, SipiläP, VesalaJ
Original Abstract of the Article :
A prospective phase II study was performed to evaluate the effect and tolerability of a peroral combination chemotherapy consisting of hexamethylmelamine, cyclophosphamide, and carmofur in patients with epithelial ovarian cancer previously heavily treated by cisplatin-based chemotherapy but no longe...See full text at original site
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引用元:
https://doi.org/10.1016/0090-8258(89)90099-1
データ提供:米国国立医学図書館(NLM)
Second-Line Therapy for Advanced Ovarian Cancer: A Desert Oasis of Hope
Advanced epithelial ovarian cancer poses a significant challenge in the fight against cancer. This phase II study, like a camel navigating the arid landscape of cancer treatment, explored the effectiveness and tolerability of a peroral combination chemotherapy regimen consisting of hexamethylmelamine, cyclophosphamide, and carmofur in patients with ovarian cancer who had previously failed to respond to cisplatin-based chemotherapy. The study aimed to provide a lifeline of hope for patients with limited treatment options.A New Path in the Desert of Cancer Treatment: Exploring Alternative Therapies
The study's findings, like a shimmering oasis in the desert, offer a glimmer of hope for patients with advanced ovarian cancer. The study demonstrated that the peroral combination chemotherapy regimen was generally well-tolerated and resulted in clinical complete remission in one patient and partial remission in four patients, providing a window of opportunity for disease control and improved survival. This finding underscores the importance of exploring alternative treatment strategies for patients with limited options.Navigating the Cancer Treatment Landscape: Hope and Resilience
For patients facing advanced ovarian cancer, understanding the range of treatment options available is essential. This study highlights the potential of alternative chemotherapy regimens to offer a lifeline of hope and improve survival outcomes. It's like finding a hidden oasis in the desert, where resources and support can help patients navigate the challenges of their journey.Dr. Camel's Conclusion
This phase II study, like a compassionate guide leading a caravan through a harsh desert, offers a beacon of hope for patients with advanced ovarian cancer. The study's findings demonstrate the potential of a peroral combination chemotherapy regimen to provide clinical benefit and improve survival, offering a valuable alternative for patients with limited treatment options. As a researcher, I am encouraged by the study's results and the potential they hold for expanding our understanding of cancer treatment and improving patient outcomes.Date :
- Date Completed 1989-07-28
- Date Revised 2021-08-26
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