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Dehydroepiandrosterone (DHEA): hypes and hopes.

Author: Kuryliszyn-MoskalAnna, Rutkowska-TalipskaJoanna, RutkowskiKrzysztof, RutkowskiRyszard, SowaPaweł

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Dehydroepiandrosterone (DHEA) is a hormone that declines with age. This review discusses the potential benefits of DHEA supplementation in humans. The review found that DHEA may have some benefits for the elderly, including improved physical and mental well-being, increased muscle strength, and reduced body fat. The review also found that DHEA may be beneficial for patients with adrenal insufficiency, systemic lupus erythematosus, and inflammatory bowel disease. However, the review emphasizes that more research is needed to determine the optimal dose and long-term safety of DHEA supplementation.
Paper Details　
Original Abstract of the Article :
Dehydroepiandrosterone (DHEA) and its sulfated form dehydroepiandrosterone sulfate (DHEAS) are the most abundant circulating steroid hormones in humans. In animal studies, their low levels have been associated with age-related involuntary changes, including reduced lifespan. Extrapolation of animal ...See full text at original site
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引用元：
https://doi.org/10.1007/s40265-014-0259-8

データ提供：米国国立医学図書館（NLM）

DHEA: More Than Just a Hype

This study focuses on the hormone dehydroepiandrosterone (DHEA) and its potential role in human health. DHEA, once touted as an 'anti-aging' panacea, has garnered significant attention in recent years. The authors examine the scientific evidence supporting DHEA's potential benefits in various conditions, including aging, adrenal insufficiency, and autoimmune diseases. They also acknowledge the challenges in interpreting research findings, such as the use of animal models and variations in dosage protocols.

DHEA: A Potential Ally in Aging and Beyond

The research suggests that DHEA might hold potential for addressing various health challenges related to aging, adrenal insufficiency, and autoimmune disorders. While more research is needed to establish optimal dosing protocols and confirm its efficacy, DHEA shows promise as a potential therapeutic agent for a range of conditions. It's like finding a hidden oasis in the vast desert of aging-related health issues.

Navigating the Desert of DHEA Research

This study highlights the importance of conducting large-scale, well-designed clinical trials to fully understand the potential benefits and risks of DHEA. It cautions against over-reliance on animal models and emphasizes the need for individualized dosing approaches. As we venture deeper into the desert of DHEA research, we must be cautious and thorough, ensuring that we extract valuable insights and avoid mirages.

Dr.Camel's Conclusion

The desert of DHEA research is vast and complex. This research provides a valuable roadmap, pointing out potential oases of benefits while warning against the dangers of mirages. It reminds us that the journey for scientific truth requires patience, rigor, and a keen eye for detail.

Date :
  1. Date Completed 2015-06-22
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

25022952

DOI: Digital Object Identifier

10.1007/s40265-014-0259-8

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English

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