Paper Details

  1. Home
  2. Paper Details

Should we still be concerned about the potential side effects of glucagon-like peptide-1 receptor agonists on thyroid C cells?

Author: CaoYang, LiuXiao-Min

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

GLP-1R agonists are a new class of drugs that are used to treat type 2 diabetes. They work by mimicking a hormone called GLP-1, which helps to regulate blood sugar levels. While GLP-1R agonists have been shown to be effective and safe, there are still some concerns about their potential side effects, especially on thyroid C cells. This review discusses the current evidence on the safety of GLP-1R agonists and calls for further research to address these concerns.
Paper Details　
Original Abstract of the Article :
In recent years, numerous novel anti-diabetic drugs have emerged. Among them, glucagon-like peptide-1 receptor (GLP-1R) agonists developed on the basis of the incretin theory are the most popular and surprising. Thus far, the clinical and experimental efficiency and safety data seem to be good. Howe...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/s12020-014-0354-3

データ提供：米国国立医学図書館（NLM）

GLP-1R Agonists and Thyroid C Cells: A Closer Look at Potential Side Effects

Glucagon-like peptide-1 receptor (GLP-1R) agonists are a popular new class of drugs used to treat diabetes. While their effectiveness and safety have been generally positive, concerns remain about their potential impact on thyroid C cells, which play a role in calcium regulation.

Navigating the Complexities of GLP-1R Agonists

Animal studies have shown potential risks of GLP-1R agonists on thyroid C cells. However, human studies have yielded conflicting results, and long-term data is still lacking. The complex interplay of various factors, including GLP-1R and other influencing factors, makes it challenging to draw definitive conclusions about the impact of GLP-1R agonists on thyroid C cells.

The Need for Continued Monitoring and Research

This research emphasizes the importance of continued monitoring and research to fully understand the potential side effects of GLP-1R agonists on thyroid C cells. Long-term studies and detailed analysis of human tissue samples are crucial for addressing these concerns and ensuring the safe and effective use of these drugs.

Dr.Camel's Conclusion

This study highlights the importance of thorough research and monitoring to understand the long-term effects of GLP-1R agonists on thyroid C cells. Continued investigation is crucial to ensuring the safety and efficacy of these widely used diabetes medications.

Date :
  1. Date Completed 2015-11-11
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

25033998

DOI: Digital Object Identifier

10.1007/s12020-014-0354-3

Related Literature

Article Analysis
・Side Effects of thyroid
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.