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Acute lymphoblastic leukemia in a patient with pituitary dwarfism under treatment with growth hormone.

Author: AkabaneT, HaraT, KomiyamaA, OnoH

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

An 18-year-old male with pituitary dwarfism who was receiving growth hormone (GH) replacement therapy developed acute lymphoblastic leukemia (ALL). After discontinuing GH, the patient achieved complete remission after 10 weeks of treatment, but experienced slow recovery of hemoglobin and white blood cell count. This suggests that GH may play a role in the proliferation of some normal and leukemic hemato-lymphoid cells.
Paper Details　
Original Abstract of the Article :
An 18-year-old male with pituitary dwarfism, who had been on replacement of growth hormone (GH) and thyroxine for 3.5 years, developed acute lymphoblastic leukemia (ALL). The GH replacement was discontinued, and he was treated with a conventional protocol for ALL. A complete remission was obtained a...See full text at original site
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引用元：
https://doi.org/10.1111/j.1442-200x.1989.tb01272.x

データ提供：米国国立医学図書館（NLM）

Acute Lymphoblastic Leukemia and Growth Hormone: A Complex Interplay

Acute lymphoblastic leukemia (ALL), a type of cancer affecting blood-forming cells, can be like a sudden desert storm, disrupting the body's delicate balance. This case study examines the relationship between ALL and growth hormone (GH) in a patient with pituitary dwarfism. The authors investigate the effects of GH on the course of ALL treatment. They seek to understand [主な目的] and uncover any potential connections between GH and ALL. They found that [主要な発見], suggesting [研究分野における影響].

Growth Hormone and Leukemia: A Balancing Act

The research highlights the intricate interplay between growth hormone and acute lymphoblastic leukemia, emphasizing the need for careful management in patients with both conditions. While GH is crucial for growth and development, it can also influence the behavior of certain cells, potentially affecting the course of leukemia treatment. The study suggests that [研究結果] and emphasizes the importance of personalized approaches to managing these conditions.

Navigating the Desert of Leukemia: A Multifaceted Approach

If you or a loved one is facing a diagnosis of ALL, it's crucial to seek expert medical advice and collaborate closely with your healthcare team. Just as navigating a desert requires careful planning and adaptation, managing leukemia requires a multidisciplinary approach. The research underscores the complexity of this disease and highlights the ongoing need for research to develop safer and more effective treatments.

Dr.Camel's Conclusion

This case study reminds us that the desert of medicine is full of intricate connections, and we must navigate it with care and precision. The interplay between growth hormone and leukemia is a complex one, requiring a careful approach to treatment. The study provides valuable insights into this complex relationship, emphasizing the importance of individualizing care and remaining vigilant in our pursuit of better treatment options.
Date :
  1. Date Completed 1989-09-15
  2. Date Revised 2019-09-12
Further Info :

Pubmed ID

2504031

DOI: Digital Object Identifier

10.1111/j.1442-200x.1989.tb01272.x

Related Literature

Article Analysis
・Effective treatment of dwarfism
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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