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Evaluating the safety and efficacy of dextromethorphan/quinidine in the treatment of pseudobulbar affect.

Author: MorrowSarah A, SchoedelKerri A, SellersEdward M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Dextromethorphan/quinidine (DM/Q) is a combination product indicated for the treatment of pseudobulbar affect (PBA). Three studies have shown significant effects on the primary end point, the Center for Neurologic Study-Lability Scale, and secondary efficacy endpoints.
Paper Details　
Original Abstract of the Article :
Pseudobulbar affect (PBA) is a common manifestation of brain pathology associated with many neurological diseases, including amyotrophic lateral sclerosis, Alzheimer's disease, stroke, multiple sclerosis, Parkinson's disease, and traumatic brain injury. PBA is defined by involuntary and uncontrollab...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079824/

データ提供：米国国立医学図書館（NLM）

Treating Pseudobulbar Affect: Dextromethorphan/Quinidine

Navigating the complexities of neurological disorders can be a challenging journey, and pseudobulbar affect (PBA) is a condition that often complicates these journeys. This study explores the use of dextromethorphan/quinidine (DM/Q) as a potential treatment for PBA. Think of it like finding a new oasis in a desert—a place where those struggling with PBA might find relief and improved well-being.

DM/Q for PBA

The research found that DM/Q was effective in treating PBA, leading to significant improvements in patient symptoms. It's like providing the camel with a refreshing drink in the desert, helping it overcome the challenges of the journey. The researchers also discussed the potential safety concerns associated with DM/Q, highlighting the importance of careful monitoring and appropriate patient selection.

Managing PBA

The study's findings offer a potential treatment option for PBA, a condition that can significantly impact the quality of life for those affected. It's like finding a new route across a challenging desert landscape—offering a path towards better health and well-being. This research underscores the need for careful consideration and individualized approaches when treating neurological disorders, ensuring that patients receive the most appropriate and effective care.

Dr.Camel's Conclusion

This study provides a glimmer of hope for individuals struggling with PBA. While more research is needed to fully understand the nuances of DM/Q treatment, the findings suggest that this medication might offer a path towards better management of this challenging condition. It's like discovering a new oasis in the desert—a place where those with PBA might find relief and a renewed sense of well-being. This research emphasizes the importance of continuous exploration and innovation in the field of neurological medicine, ensuring that patients have access to the best possible treatments.

Date :
  1. Date Completed 2014-07-25
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

25061302

DOI: Digital Object Identifier

PMC4079824

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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