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The anxiolytic effects of a Valerian extract is based on valerenic acid.

Author: BeckerAxel, BrattströmAxel, FelgentreffFalko, MeierBeat, SchröderHelmut

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigated whether acetoxy valerenic acid interferes with the anxiolytic action of valerenic acid, a component of valerian extracts that allosterically modulates GABA-A receptors.
Paper Details　
Original Abstract of the Article :
Valerian is commonly used for the treatment of insomnia and anxiety. Valerian extracts allosterically modulate GABA-A receptors and induced an anxiolytic activity. This activity is closely related to valerenic acid. In the present experiments it was investigated whether acetoxy valerenic acid may in...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122768/

データ提供：米国国立医学図書館（NLM）

Valerian Extract: The Anxiolytic Effects of Valerenic Acid

Valerian is a popular herbal remedy used for insomnia and anxiety. It’s like a comforting oasis in the desert, offering a sense of peace and calm.

This study investigated the anxiolytic effects of valerian extract and its relationship to valerenic acid, a key active compound. The authors found that valerenic acid, but not acetoxy valerenic acid, played a significant role in the anxiolytic activity of valerian extract. It’s like a caravan leader discovering the true source of a desert spring, revealing the key to its healing power.

The study suggests that valerian extract's anxiolytic effect is mediated by valerenic acid, potentially through modulation of GABA-A receptors. It’s like a caravan finding a hidden path to a peaceful valley, guided by the wisdom of a natural remedy.

Valerian: A Potential Natural Anxiolytic

This study offers evidence for the anxiolytic potential of valerian extract, suggesting that valerenic acid is a key factor in its therapeutic effects. It’s like a camel caravan finding a new source of comfort and solace in the desert.

The Importance of Natural Remedies

This study highlights the importance of exploring natural remedies for anxiety. It’s like a caravan seeking a natural oasis, a source of peace and well-being in the midst of the challenges of life.

Dr.Camel's Conclusion

This study sheds light on the anxiolytic properties of valerian extract, suggesting that valerenic acid plays a crucial role. It’s like a camel caravan discovering a hidden spring of tranquility in the vast desert, a testament to the power of nature’s remedies.
Date :
  1. Date Completed 2014-11-14
  2. Date Revised 2021-10-21
Further Info :

Pubmed ID

25066015

DOI: Digital Object Identifier

PMC4122768

Related Literature

Article Analysis
・Effective treatment of valerian
SNS
PICO Info
in preparation
Languages

English

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