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Perioperative measures to improve outcome after subarachnoid hemorrhage-revisiting the concept of secondary brain injury.
Author: BeezThomas, BeseogluKerim, HänggiDaniel, KampMarcel A, SteigerHans-Jakob
Original Abstract of the Article :
Progress in the management of aneurysmal subarachnoid hemorrhage (SAH) is reflected most clearly in a continuously decreasing case fatality rate over the last decades. The purpose of the present review is to identify the relevant factors responsible for this progress and to outline future possibilit...See full text at original site
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引用元:
https://doi.org/10.1007/978-3-319-04981-6_36
データ提供:米国国立医学図書館(NLM)
The Shifting Sands of Secondary Brain Injury: New Insights into Subarachnoid Hemorrhage
The world of neurological emergencies is a treacherous desert, where conditions like subarachnoid hemorrhage (SAH) pose significant threats. While advancements in medical care have helped to reduce the fatality rate associated with SAH, the journey to recovery remains fraught with challenges, particularly the risk of secondary brain injury. This research delves into the complex landscape of secondary brain injury, exploring the factors that contribute to its occurrence and the potential for pharmacological intervention.
The Shifting Sands of Prevention: Targeting Secondary Brain Injury in SAH
The study underscores the crucial role of secondary brain injury in determining the long-term outcomes of SAH, a challenge akin to navigating a shifting desert landscape. While advancements in neurocritical care have contributed to improved survival rates, efforts to prevent secondary neuronal damage remain a critical focus. The research explores various pharmacological approaches, such as calcium antagonists and rho-kinase inhibitors, in an attempt to mitigate this threat. However, the study's findings suggest that, while oral nimodipine has shown some benefit, other interventions haven't yielded conclusive evidence of improving functional outcome. This highlights the need for continued research and exploration of alternative strategies to address the challenges posed by secondary brain injury in SAH.
A Journey of Continued Exploration: Navigating the Desert of Secondary Brain Injury
The research sheds light on the complex nature of secondary brain injury, emphasizing the need for a more nuanced understanding of its mechanisms and the potential for targeted interventions. While current evidence for pharmacological approaches remains limited, the journey of research continues, seeking to identify new pathways and strategies to mitigate the risks associated with secondary brain injury. This research serves as a reminder that the desert of neurological emergencies is a complex landscape, requiring ongoing exploration and innovation to ensure the best possible outcomes for those facing these challenges.
Dr.Camel's Conclusion
The research highlights the importance of understanding and managing secondary brain injury in the context of subarachnoid hemorrhage. While advancements in neurocritical care have contributed to improved survival rates, the quest for effective pharmacological interventions to prevent secondary neuronal damage remains a crucial priority. The journey through this challenging landscape requires continued exploration and innovation to find new paths toward a more hopeful future for patients.
Date :
- Date Completed 2015-03-16
- Date Revised 2014-11-04
Further Info :
Related Literature
English
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