Orexin receptor antagonists--a patent review (2010 to August 2014).

Author: BossChristoph

Paper Details 
Original Abstract of the Article :
The orexin (hypocretin) system is an evolutionarily conserved neuropeptide-G-protein-coupled receptor system, consisting of two neuropeptides the orexin-A and the orexin-B peptides as well as two receptors the orexin-1 and the orexin-2 receptors. The orexin system is crucially involved in the regula...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1517/13543776.2014.978859

データ提供:米国国立医学図書館(NLM)

Orexin Receptor Antagonists: Targeting Insomnia and Beyond

The orexin system plays a crucial role in regulating sleep-wake cycles, and targeting this system has emerged as a promising strategy for treating insomnia. This study provides a comprehensive overview of orexin receptor antagonists, focusing on patents filed from 2010 to 2014. The research explores the potential of these antagonists in treating insomnia and other neurological disorders.

Orexin Receptor Antagonists: A New Frontier in Insomnia Treatment

The study highlights the substantial interest in orexin receptor antagonists as a potential treatment for insomnia. Merck's suvorexant, a dual orexin receptor antagonist, has received FDA approval for the treatment of insomnia. This demonstrates the clinical potential of targeting the orexin system for improving sleep quality. The study also explores the potential of these antagonists in other areas, such as mood disorders and drug addiction. This research is like a journey through a new and unexplored desert, revealing the potential of orexin receptor antagonists to treat a wide range of neurological conditions.

What Does This Mean for People Struggling with Sleep?

This research provides hope for people struggling with insomnia. Orexin receptor antagonists represent a promising new approach to treating insomnia, with the potential for improved sleep quality and reduced daytime drowsiness. This research is like a map guiding us towards a future where insomnia is no longer a barrier to a healthy and productive life.

Dr.Camel's Conclusion

The desert of sleep research is vast and full of mysteries, but this research sheds light on a promising new path. Orexin receptor antagonists, like a shimmering oasis, offer hope for those struggling with insomnia. This research is a reminder that we must continue to explore the complex world of sleep and develop innovative solutions to improve the lives of those struggling with sleep disorders.

Date :
  1. Date Completed 2015-09-02
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

25407283

DOI: Digital Object Identifier

10.1517/13543776.2014.978859

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.