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Intravenous dextromethorphan/quinidine inhibits activity of dura-sensitive spinal trigeminal neurons in rats.
Author: BerkovichR R, LyubashinaO A, PanteleevS S, SokolovA Y
Original Abstract of the Article :
Migraine is a chronic neurological disorder characterized by episodes of throbbing headaches. Practically all medications currently used in migraine prophylaxis have a number of substantial disadvantages and use limitations. Therefore, the further search for principally new prophylactic antimigraine...See full text at original site
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引用元:
https://doi.org/10.1002/ejp.631
データ提供:米国国立医学図書館(NLM)
Exploring New Treatments for Migraine: Investigating the Potential of Dextromethorphan/Quinidine
Migraine is a debilitating neurological condition that affects millions of people. Current medications often have limitations, prompting researchers to explore new treatment options. This study investigates the effects of a fixed combination of [dextromethorphan hydrobromide and quinidine sulphate (DM/Q)] on the activity of [spinal trigeminal neurons] in an electrophysiological model of trigemino-durovascular nociception. The findings suggest that DM/Q may offer a promising new approach to migraine prophylaxis.
Dextromethorphan/Quinidine: A Potential Game-Changer for Migraine Prophylaxis?
The research demonstrates that DM/Q effectively inhibits the activity of spinal trigeminal neurons, potentially reducing the transmission of pain signals associated with migraine. This finding suggests that DM/Q could be a valuable new tool for migraine prophylaxis. This research, like a caravan navigating a challenging desert landscape, provides hope for finding effective and safe treatments for this debilitating condition.
Finding Relief from Migraines: Exploring New Treatment Options
This research highlights the importance of exploring new and innovative treatments for migraine. DM/Q shows promise as a potential prophylactic agent, offering a new avenue for reducing the frequency and severity of migraine attacks. This research, like a well-stocked oasis in the desert, provides hope for those seeking relief from the pain and disability associated with migraines.
Dr.Camel's Conclusion
This research, like a cool desert breeze, brings a refreshing perspective on migraine treatment. The potential of DM/Q as a migraine prophylactic agent offers hope for a more effective and tolerable approach to managing this debilitating condition.
Date :
- Date Completed 2016-08-23
- Date Revised 2018-12-02
Further Info :
Related Literature
English
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