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[Granulomatous hepatitis revealing a Mycobacterium bovis widespread infection following intravesical BCG therapy].

Author: BonnetH, DuffauP, Longy-BoursierM, RaffrayL, RivièreP

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Intravesical therapy with bacillus Calmette-Guérin (BCG) has proved to be effective in the treatment of superficial bladder tumors. Side-effects include local infections and rarely disseminated BCG infection with multiple end organ complications.
Paper Details　
Original Abstract of the Article :
Intravesical therapy with bacillus Calmette-Guérin (BCG) has proved to be effective in the treatment of superficial bladder tumors. Side-effects include local infections and rarely disseminated BCG infection with multiple end organ complications such as granulomatous hepatitis, pneumonitis, aortitis...See full text at original site
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引用元：
https://doi.org/10.1016/j.revmed.2014.10.361

データ提供：米国国立医学図書館（NLM）

A Widespread Infection: Granulomatous Hepatitis Unveils BCG Therapy Complications

Bacillus Calmette-Guérin (BCG) therapy is a widely used treatment for superficial bladder tumors, but it can also lead to complications. This case report describes a patient who developed granulomatous hepatitis, a rare but serious complication of BCG therapy. The researchers investigated the cause of this complication, highlighting the potential for BCG to cause widespread infection in the body.

BCG Therapy: A Double-Edged Sword

The case report reveals that BCG therapy, while effective for treating bladder tumors, can also lead to disseminated BCG infection, affecting multiple organs. The researchers discovered that the patient's granulomatous hepatitis was linked to a widespread BCG infection, underscoring the importance of vigilant monitoring for potential complications during BCG treatment. It's like a desert storm, initially bringing beneficial rainfall but later causing widespread damage if not carefully managed.

Navigating the Risks of BCG Therapy

This case report underscores the need for vigilance in managing patients undergoing BCG therapy. Clinicians must be aware of the potential for disseminated BCG infection and monitor patients closely for any signs of complications. It's a reminder that even the most effective treatments can carry risks, requiring careful consideration and a proactive approach to managing potential complications. Just as a camel caravan must navigate a desert with caution to avoid hazards, we must approach BCG therapy with careful observation and preparedness to address any potential risks.

Dr.Camel's Conclusion

This case report serves as a valuable reminder of the potential complications associated with BCG therapy. By understanding the risks and recognizing the importance of vigilant monitoring, clinicians can ensure the safety and effectiveness of this treatment for bladder cancer patients.

Date :
  1. Date Completed 2016-06-29
  2. Date Revised 2016-10-18
Further Info :

Pubmed ID

25467298

DOI: Digital Object Identifier

10.1016/j.revmed.2014.10.361

SNS
PICO Info
in preparation
Languages

French

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