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Streptozotocin-nicotinamide-induced rat model of type 2 diabetes (review).

Author: GhasemiAsghar, JediS, KhalifiS

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study provides an overview of the streptozotocin and nicotinamide-induced rat model of type 2 diabetes, a commonly used model in diabetes research. It highlights the model's advantages and disadvantages for studying diabetes in humans.
Paper Details　
Original Abstract of the Article :
Diabetes is one of the five leading causes of death in the world, with type 2 diabetes occurring more frequently than type 1. Management of diabetes without side effects is still a challenge and therefore new strategies need to be examined. Because of difficulties in human research, animal models of...See full text at original site
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引用元：
https://doi.org/10.1556/APhysiol.101.2014.4.2

データ提供：米国国立医学図書館（NLM）

Streptozotocin-Nicotinamide Model: A Valuable Tool for Type 2 Diabetes Research

Type 2 diabetes is a growing global health concern, much like the expanding desert sands. This study reviews the streptozotocin-nicotinamide-induced rat model of type 2 diabetes, a valuable tool for studying this complex disease. The study aimed to assess the advantages and disadvantages of this model in relation to human diabetes research.

A Versatile Model for Diabetes Research

The study highlights the streptozotocin-nicotinamide model as a widely used and versatile tool for studying type 2 diabetes in rats. The model mimics key features of human type 2 diabetes, providing researchers with a valuable platform for investigating potential therapies and understanding the disease's pathogenesis.

Understanding and Managing Diabetes

Diabetes, much like a desert ecosystem, requires a delicate balance to maintain health. The study underscores the importance of animal models in advancing diabetes research. The streptozotocin-nicotinamide model offers a valuable platform for exploring new treatments and strategies for managing this complex disease.

Dr.Camel's Conclusion

This research provides a comprehensive overview of the streptozotocin-nicotinamide-induced rat model of type 2 diabetes. The study underscores the model's value in advancing diabetes research and its potential to contribute to the development of new and effective therapies.

Date :
  1. Date Completed 2015-03-11
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

25532953

DOI: Digital Object Identifier

10.1556/APhysiol.101.2014.4.2

Related Literature

Article Analysis
・Side Effects of streptozocin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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