Safety and efficacy of alirocumab 150 mg every 2 weeks, a fully human proprotein convertase subtilisin/kexin type 9 monoclonal antibody: A Phase II pooled analysis.

Author: DufourRobert, FerrandAnne-Catherine, GipeDaniel, HanotinCorinne, KorenMichael J, McKenneyJames M, RothEli M, WuRichard

Paper Details 
Original Abstract of the Article :
Alirocumab, a fully human monoclonal antibody to proprotein convertase subtilisin/kexin type 9, is in Phase III development for the treatment of hypercholesterolemia. In Phase II studies, 150 mg every 2 weeks (Q2W) was the highest Q2W dose studied, and it is currently the highest Q2W dose under deve...See full text at original site
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引用元:
https://doi.org/10.1080/00325481.2015.998987

データ提供:米国国立医学図書館(NLM)

Safety and efficacy of alirocumab 150 mg every 2 weeks, a fully human proprotein convertase subtilisin/kexin type 9 monoclonal antibody: A Phase II pooled analysis

High cholesterol is a silent threat, lurking beneath the surface like a desert sandstorm. This study investigates the safety and efficacy of alirocumab, a new type of medication designed to lower cholesterol levels, in patients with high cholesterol. The researchers pooled data from three Phase II studies to provide a comprehensive assessment of this promising treatment option.

Navigating the Cholesterol Desert

The pooled analysis suggests that alirocumab, when administered at a dose of 150 mg every 2 weeks, is both safe and effective in lowering cholesterol levels. This research provides valuable data for future studies and helps guide clinicians in making informed decisions about the use of alirocumab for patients with high cholesterol.

Combating Cholesterol's Silent Threat

This study offers a valuable tool for clinicians seeking to combat the silent threat of high cholesterol. The findings provide evidence that alirocumab can be a safe and effective treatment option for patients, helping them navigate the challenging terrain of cardiovascular health.

Dr.Camel's Conclusion

This research, like a compass guiding us through the desert of cardiovascular health, provides valuable information about the safety and efficacy of alirocumab. It helps us understand the potential benefits and risks of this new treatment option, paving the way for better management of high cholesterol and improved cardiovascular health for patients.

Date :
  1. Date Completed 2015-09-08
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

25609019

DOI: Digital Object Identifier

10.1080/00325481.2015.998987

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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