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Therapeutic development in amyotrophic lateral sclerosis.

Author: BucchiaMonica, CortiStefania, DamettiSara, MagriFrancesca, NizzardoMonica, ParenteValeria, RamirezAgnese, SimoneChiara

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Amyotrophic lateral sclerosis (ALS) is a common nerve disease that is fatal within a few years. While there is no effective cure, recent research has focused on understanding the disease and potential treatments. The review examines new treatments under development, highlighting their specific targets within the body.
Paper Details　
Original Abstract of the Article :
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in adults. It is almost invariably lethal within a few years after the onset of symptoms. No effective treatment is currently available beyond supportive care and riluzole, a putative glutamate release blocker linked to mode...See full text at original site
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引用元：
https://doi.org/10.1016/j.clinthera.2014.12.020

データ提供：米国国立医学図書館（NLM）

Therapeutic Development in Amyotrophic Lateral Sclerosis: A Journey Through the Desert

Amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease, is like a relentless desert wind, slowly eroding the body's motor function. This study, like a caravan of researchers seeking a cure in a vast and unforgiving desert, explores the current state of therapeutic development for ALS.

The researchers provide a comprehensive overview of preclinical and clinical advances in ALS research, highlighting the various molecular targets and treatment approaches being investigated. This research effort, like a meticulously crafted map, guides the path toward potential cures and therapies for this debilitating disease.

A Desert Oasis of Hope: Seeking New Therapies for ALS

The study highlights the ongoing efforts to develop effective treatments for ALS, offering a glimmer of hope for those affected by this disease. These efforts, like a caravan seeking a hidden oasis, are driven by a commitment to finding solutions and improving the lives of patients.

Dr. Camel's Conclusion

This review underscores the challenges and opportunities in ALS research. The quest for a cure is a long and arduous journey, like a camel traversing a vast and unforgiving desert. Yet, the dedication of researchers, like a beacon of hope shining in the night, provides a source of inspiration and motivation for those seeking to conquer this devastating disease.

Date :
  1. Date Completed 2016-03-29
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25666449

DOI: Digital Object Identifier

10.1016/j.clinthera.2014.12.020

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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