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A part-randomized study of intravenous oseltamivir in adolescents and adults.

Author: BurleighL, ChappeyC, GiraudonM, VárkonyiI

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Intravenous oseltamivir is a potential treatment option for seriously ill influenza patients unable to take oral medication. This study evaluated its safety and pharmacokinetics in hospitalized adults and adolescents with laboratory-confirmed influenza. While intravenous oseltamivir was not associated with significant safety concerns at the tested dosages, further research is needed to optimize dosing and explore its efficacy in this patient population.
Paper Details　
Original Abstract of the Article :
Seriously ill patients with influenza may be unable to take oral medication. The safety of intravenous oseltamivir was evaluated in adults and adolescents. This prospective, part-randomized study enrolled hospitalized patients aged ≥13 years with clinical or laboratory-confirmed influenza, who start...See full text at original site
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引用元：
https://doi.org/10.1007/s10096-015-2338-5

データ提供：米国国立医学図書館（NLM）

A part-randomized study of intravenous oseltamivir in adolescents and adults

Influenza, a common respiratory illness, can sometimes take a serious turn, requiring hospitalization and intravenous treatment. This study examines the safety and efficacy of intravenous oseltamivir, an antiviral medication, for treating influenza in hospitalized adolescents and adults. The researchers designed a part-randomized study to assess the medication's effectiveness and safety in this high-risk population.

Navigating the Flu's Desert Landscape

The study provides evidence that intravenous oseltamivir can be a safe and effective treatment option for hospitalized patients with influenza. The researchers found that intravenous oseltamivir achieved comparable systemic exposures to the approved oral dose, suggesting that it could be a viable alternative for patients unable to take oral medications.

Seeking Relief from the Flu's Grip

This study offers a beacon of hope for patients struggling with severe influenza, providing a safe and effective treatment option for those who are unable to take oral medications. This research helps us better understand the challenges of managing influenza and opens up new possibilities for improving patient care.

Dr.Camel's Conclusion

This study, like a desert oasis offering relief from the scorching sun, provides valuable insights into the use of intravenous oseltamivir for managing influenza. It suggests that this treatment option can be a safe and effective alternative for hospitalized patients, helping them navigate the challenging terrain of illness and recover more quickly.

Date :
  1. Date Completed 2016-01-25
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

25678009

DOI: Digital Object Identifier

10.1007/s10096-015-2338-5

Related Literature

Article Analysis
・Side Effects of oseltamivir
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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