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Subjective and Objective Effects of Androgen Ablation Therapy on Voice.
Author: AydoğduÏmran, KumralTolgar Lütfi, SalturkZiya, UyarYavuz, YıldırımGüven, ÇakırOzan, ÖtünçtemurAlper
Original Abstract of the Article :
OBJECTIVES: The aim of present study was to evaluate possible side effects of androgen deprivation therapy (ADT) on voice quality by means of objective and subjective measures. STUDY DESIGN: Cross-sectional. METHODS: Thirty-five male patients who had been diagnosed with prostate cancer and who had...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.jvoice.2014.09.010
データ提供:米国国立医学図書館(NLM)
The Impact of Androgen Ablation Therapy on Voice Quality
The field of [oncology] is constantly seeking to understand the intricate effects of treatments on the human body. This study dives into the potential side effects of [androgen deprivation therapy (ADT)] on voice quality, a subject that can significantly impact a patient's well-being. Using a [cross-sectional] study design, the researchers meticulously analyzed [35 male patients diagnosed with prostate cancer] who had been undergoing ADT for at least a year. Their findings shed light on the complex relationship between ADT and voice quality, revealing a potential for adverse effects. The researchers observed a significant decrease in [maximum phonation time] in the ADT group compared to the control group, suggesting a possible impact on vocal endurance. Additionally, they noted significantly higher values for [fundamental frequency, jitter, and shimmer] in the ADT group, hinting at a potential alteration in vocal pitch and stability. These observations emphasize the importance of considering the potential vocal consequences of ADT and underscores the need for further investigation.
ADT's Potential Vocal Impact: A Desert Oasis of Insight
The study's findings suggest that ADT might have an adverse impact on the human voice, potentially leading to [reduced vocal endurance, altered pitch, and increased vocal instability]. While these effects are significant, it's essential to remember that this study involved a relatively small sample size and requires further investigation to solidify these findings. This study serves as a crucial reminder of the importance of addressing potential side effects of medical treatments, especially those impacting daily life and communication.
A Symphony of Challenges and Opportunities for Research
Just like a camel navigating a vast desert, researchers are diligently exploring the complexities of ADT and its vocal implications. The study highlights the need for further research, especially [prospective studies with long-term follow-up] of a larger patient population. This would allow for a more comprehensive understanding of the long-term effects of ADT on voice quality and pave the way for developing strategies to mitigate potential adverse effects. By unraveling the intricacies of ADT's impact, researchers can create a roadmap for improving patient care and ensuring a smoother journey through treatment.
Dr. Camel's Conclusion
This research acts as a compass guiding us towards a deeper understanding of the intricate relationship between ADT and voice quality. While we've uncovered potential vocal side effects, we are only at the beginning of our journey. Future research will be crucial to explore these effects further and develop strategies to ensure the well-being of patients undergoing ADT. Remember, like the vast desert, the world of medical research is full of surprises, and we must be prepared to adapt and learn with each new discovery.
Date :
- Date Completed 2016-04-14
- Date Revised 2015-06-29
Further Info :
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