Treatment of pain at sexual activity (dyspareunia) with intravaginal dehydroepiandrosterone (prasterone).

Author: , ArcherDavid F, BalserJohn, BouchardCéline, CusanLeonello, CôtéIsabelle, KoltunWilliam, LabrieClaude, LabrieFernand, LavoieLyne, MartelCéline, PortmanDavid J

Paper Details 
Original Abstract of the Article :
OBJECTIVE: This study aims to confirm the local effects of intravaginal prasterone on moderate to severe dyspareunia, a symptom of vulvovaginal atrophy (VVA) associated with menopause. METHODS: In a prospective, randomized, double-blind, placebo-controlled phase III clinical trial, we examined the ...See full text at original site
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引用元:
https://doi.org/10.1097/GME.0000000000000428

データ提供:米国国立医学図書館(NLM)

Intravaginal Prasterone: A New Approach to Treating Dyspareunia

Dyspareunia, painful intercourse, is a common symptom of vulvovaginal atrophy (VVA), a condition often associated with menopause. This research explores the effectiveness of intravaginal prasterone, a form of dehydroepiandrosterone, in treating moderate to severe dyspareunia. They conducted a double-blind, placebo-controlled clinical trial with women experiencing dyspareunia, comparing the effects of daily intravaginal prasterone to a placebo over a 12-week period.

A Promising Treatment Option

The study showed that intravaginal prasterone led to significant improvements in several key indicators of VVA, including a decrease in parabasal cells, an increase in superficial cells, a reduction in vaginal pH, and a decrease in the severity of dyspareunia. These findings suggest that intravaginal prasterone may be an effective treatment for women experiencing dyspareunia associated with VVA.

Improving Quality of Life

This study offers hope for women struggling with dyspareunia, providing a potential treatment that can improve their quality of life and intimacy. The positive outcomes of this research highlight the importance of developing targeted treatments for women's health issues, particularly those associated with menopause. It is like a camel finding a refreshing oasis in the midst of a barren desert, providing a much-needed source of comfort and relief.

Dr.Camel's Conclusion

This research provides compelling evidence for the effectiveness of intravaginal prasterone in treating dyspareunia associated with VVA. The study demonstrates that this treatment can lead to significant improvements in vaginal health and a reduction in the severity of dyspareunia. The findings encourage further investigation into the long-term effects and safety of this treatment option.

Date :
  1. Date Completed 2016-04-20
  2. Date Revised 2015-08-25
Further Info :

Pubmed ID

25734980

DOI: Digital Object Identifier

10.1097/GME.0000000000000428

Related Literature

SNS
PICO Info
in preparation
Languages

English

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