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Central nervous system effects of antihistamines on evoked potentials.

Author: LoringD W, MeadorK J

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Terfenadine produces significantly less cognitive slowing than chlorpheniramine, supporting the subjective findings of reduced sedative side effects.
Paper Details　
Original Abstract of the Article :
Sedation is the most common side effect of antihistamine therapy. As with many behavioral constructs, attempts at quantification are difficult, and consequently, subjective reports of antihistamine sedation are frequently relied upon. Evoked potential activity is one method to quantitate the brain's...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2574552

データ提供：米国国立医学図書館（NLM）

Antihistamines and Evoked Potentials: Exploring Cognitive Effects

Sedation is a common side effect of antihistamine therapy. This study investigates the cognitive effects of antihistamines, specifically chlorpheniramine and terfenadine, using evoked potentials, a measure of brain activity. The study examines the latency of the P3 evoked potential, a component related to cognitive processing, to assess the cognitive slowing induced by these medications.

Cognitive Effects of Antihistamines: A Closer Look

This study provides valuable insights into the cognitive effects of antihistamines, exploring the relationship between medication use and cognitive slowing. The research highlights the potential for different antihistamines to have varying degrees of impact on cognitive function. The study underscores the importance of considering potential cognitive side effects when prescribing antihistamines, particularly in individuals engaging in activities that require alertness and cognitive performance.

Antihistamines: Navigating the Desert of Cognitive Function

Imagine a vast and intricate desert landscape, representing the complex network of cognitive functions. This study explores the impact of antihistamines on this landscape, highlighting the potential for these medications to disrupt cognitive processes. The research emphasizes the importance of understanding the potential cognitive effects of medications, particularly those that affect the central nervous system.

Dr.Camel's Conclusion

This study investigates the cognitive effects of antihistamines, specifically chlorpheniramine and terfenadine, using evoked potentials to measure brain activity. The research highlights the potential for different antihistamines to have varying degrees of impact on cognitive function. This study underscores the importance of considering potential cognitive side effects when prescribing antihistamines, particularly in individuals engaging in activities that require alertness and cognitive performance.
Date :
  1. Date Completed 1990-01-22
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2574552

DOI: Digital Object Identifier

2574552

Related Literature

Article Analysis
・Side Effects of chlorpheniramine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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