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D2 dopamine receptor regulation of learning, sleep and plasticity.

Author: FrançaA S C, JeronimoS M B, Lobão-SoaresB, MuratoriL, NascimentoG, PereiraC M, RibeiroS, WinneJ

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Dopamine and REM sleep are both linked to hippocampus-dependent learning. This study found that blocking dopamine receptors reduced REM sleep and impaired learning in mice. This suggests that dopamine's influence on learning may be mediated through its role in regulating REM sleep.
Paper Details　
Original Abstract of the Article :
Dopamine and sleep have been independently linked with hippocampus-dependent learning. Since D2 dopaminergic transmission is required for the occurrence of rapid-eye-movement (REM) sleep, it is possible that dopamine affects learning by way of changes in post-acquisition REM sleep. To investigate th...See full text at original site
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引用元：
https://doi.org/10.1016/j.euroneuro.2015.01.011

データ提供：米国国立医学図書館（NLM）

The Role of D2 Dopamine Receptors in Learning and Sleep: A Journey Through the Desert of Cognition

The relationship between dopamine, sleep, and learning is as complex as a desert ecosystem, with intricate connections and delicate balances. This study explores the role of D2 dopamine receptors in regulating learning, sleep, and plasticity in mice, navigating the intricate desert landscape of cognitive processes. The authors investigate the potential link between D2 dopaminergic transmission and REM sleep, a crucial element in memory consolidation and learning.

Navigating the Sands of Memory Formation

The study reveals a significant link between D2 dopamine receptors and REM sleep, highlighting the importance of this specific type of sleep in learning and memory consolidation. The authors, like desert explorers, uncover the intricate pathways by which D2 receptors influence both cognitive processes and sleep patterns. The study underscores the need for further research into the role of dopamine and sleep in learning and memory, a quest for understanding the complexities of the desert of cognition.

A Desert of Intricacies, an Oasis of Understanding

This study delves into the intricate interplay of dopamine, sleep, and learning, a complex desert landscape of cognitive processes. The authors, like skilled desert guides, reveal the crucial role of D2 dopamine receptors in navigating this intricate terrain. The study underscores the need for continued research in this area, a journey of discovery that holds the potential to unlock new insights into the mysteries of learning and memory.

Dr. Camel's Conclusion

This study reminds us that the journey through the desert of learning and memory is a complex and often unpredictable one. It's like a camel caravan, navigating shifting sands and encountering unexpected challenges along the way. The study underscores the importance of continued research in this area, a quest for understanding the intricacies of these crucial cognitive processes.

Date :
  1. Date Completed 2016-01-11
  2. Date Revised 2015-04-20
Further Info :

Pubmed ID

25778861

DOI: Digital Object Identifier

10.1016/j.euroneuro.2015.01.011

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