Effect of transdermal hormone therapy on platelet haemostasis in menopausal women.

Author: Pertyńska-MarczewskaMagdalena, PertyńskiTomasz, StachowiakGrzegorz

Paper Details 
Original Abstract of the Article :
INTRODUCTION: Despite the undeniably positive effect on the quality of life of menopausal women, menopausal hormone therapy (HT) also has negative side-effects, which include, among others, thromboembolic complications. OBJECTIVE: To assess the effect of a popular type of this therapy - transdermal...See full text at original site
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引用元:
https://doi.org/10.5604/12321966.1141389

データ提供:米国国立医学図書館(NLM)

Hormones in the Desert: Transdermal Hormone Therapy and Platelet Hemostasis

Imagine a camel navigating a desert landscape, facing the challenges of heat, thirst, and shifting sands. That's a bit like the journey of women through menopause, with hormonal changes impacting their bodies and well-being. This study investigates the effects of transdermal hormone therapy (HT) on platelet hemostasis, a crucial aspect of blood clotting, in menopausal women. The researchers compared the effects of transdermal HT with and without low-dose acetylsalicylic acid (ASA) on platelet function, examining the potential risks and benefits of this treatment.

Navigating the Desert of Menopause: Transdermal Hormone Therapy and Platelet Hemostasis

The study found that transdermal HT, in the form of combined estrogen-progestogen patches, favorably modified platelet hemostasis in postmenopausal women. The researchers observed a decrease in platelet count and a reduction in the activity of GP IIb/IIIa, a platelet receptor involved in clotting. They also found that the use of low-dose ASA was not necessary for thromboprophylaxis in short-term transdermal HT. These findings provide valuable insights into the potential impact of transdermal HT on platelet function.

A Desert Oasis of Hormonal Balance: Exploring the Effects of Transdermal Hormone Therapy

This study offers a comprehensive look at the effects of transdermal HT on platelet function in menopausal women. It highlights the importance of considering the potential risks and benefits of this treatment, particularly for women with pre-existing cardiovascular conditions. It's like navigating a desert landscape, where understanding the terrain and taking appropriate precautions can make all the difference in ensuring a safe and successful journey.

Dr.Camel's Conclusion

This study offers valuable insights into the effects of transdermal HT on platelet hemostasis in menopausal women. It's a reminder that the desert of hormonal changes can be challenging, but careful navigation and understanding the risks and benefits of different treatment options can lead to a smoother and healthier journey.

Date :
  1. Date Completed 2015-12-01
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

25780849

DOI: Digital Object Identifier

10.5604/12321966.1141389

Related Literature

SNS
PICO Info
in preparation
Languages

English

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