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Effects of S-596 and carteolol, new beta-adrenergic blockers, and flurbiprofen on the human eye: a fluorophotometric study.

Author: AraieM, TakaseM

Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Both S-596 and carteolol, new beta-adrenergic blockers, increase iris permeability and decrease aqueous flow rate. Flurbiprofen, a nonsteroidal anti-inflammatory drug, can suppress the disruption of the blood-aqueous barrier after cataract surgery.
Paper Details　
Original Abstract of the Article :
The effects of S-596 and coarteolol, new beta-adrenergic blockers, were studied by means of the oral fluorescein method. Transfer coefficients by diffusion, kd.pa, and by flow, kfa, were estimated in a total of 11 normal young volunteers, in whom the drug was instilled in one eye and the placebo in ...See full text at original site
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引用元：
https://doi.org/10.1007/BF02133693

データ提供：米国国立医学図書館（NLM）

Investigating the Effects of Beta-Adrenergic Blockers on the Human Eye

This research delves into the effects of beta-adrenergic blockers on the human eye, specifically focusing on S-596 and carteolol. Similar to a camel's ability to navigate the desert's harsh environment, the researchers have been studying the impact of these medications on the delicate structures of the eye.

A Closer Look at Eye Permeability

The study meticulously examines the effects of S-596 and carteolol on iris permeability and aqueous flow rate, using a fluorophotometric method. The researchers' findings, like a magnifying glass revealing the intricate details of the desert landscape, show that both S-596 and carteolol significantly alter the permeability of the blood-aqueous barrier.

Protecting the Eyes in a Changing Environment

This study provides valuable insights into the potential effects of beta-adrenergic blockers on the eye. The researchers' findings serve as a reminder that even seemingly simple medications can have unforeseen consequences on the delicate balance of the eye's environment.

Dr.Camel's Conclusion

This study is like a journey through the desert's delicate ecosystem, highlighting the importance of understanding the potential impacts of medications on the human eye. The researchers' meticulous investigation provides valuable insights into the effects of beta-adrenergic blockers, reminding us that careful consideration and monitoring are essential for maintaining eye health.

Date :
  1. Date Completed 1985-05-16
  2. Date Revised 2019-09-03
Further Info :

Pubmed ID

2579877

DOI: Digital Object Identifier

10.1007/BF02133693

Related Literature

Article Analysis
・Effects of flurbiprofen ophthalmic
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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