Paper Details

  1. Home
  2. Paper Details

New-Onset Diabetes and Antiretroviral Treatments in HIV-Infected Adults in Thailand.

Author: BowonwatanuwongChureeratana, CapeauJacqueline, ChutanuntaApichat, CresseyTim R, DeckerLuc, JourdainGonzague, KantipongPacharee, KlinbuayaemVirat, LallemantMarc, Le CœurSophie, LeenasirimakulPrattana, MaryJean-Yves, Ngo-Giang-HuongNicole, NilmanatAmpaipith, RiyatenPrakit, SalvadoriNicolas, TechapornroongMalee, ThongpaenSuchart, TraisathitPatrinee, YutthakasemsuntNaruepon

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The incidence of diabetes in a large cohort of HIV-infected adults in Thailand was relatively low, but those exposed to stavudine + didanosine or cumulative exposure ≥ 1 year to zidovudine had a significantly higher risk of diabetes. Cumulative exposure ≥ 1 year to tenofovir and emtricitabine was associated with a lower risk of diabetes.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Use of several antiretrovirals (ARVs) has been shown to be associated with a higher risk of diabetes in HIV-infected adults. We estimated the incidence of new-onset diabetes and assessed the association between individual ARVs and ARV combinations, and diabetes in a large cohort in Thail...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1097/QAI.0000000000000647

データ提供：米国国立医学図書館（NLM）

Antiretroviral Treatment and the Risk of Diabetes in HIV-Infected Adults

[Antiretroviral treatment] has revolutionized the management of [HIV infection], but its use has also been linked to an increased risk of [diabetes] in some patients. This study examines the incidence of [new-onset diabetes] and investigates the association between specific [antiretrovirals (ARVs)] and [ARV combinations] and the development of [diabetes] in a large cohort of [HIV-infected adults] in Thailand. The researchers found that [stavudine + didanosine] and [cumulative exposure ≥ 1 year to zidovudine] were associated with a higher risk of [diabetes], while [cumulative exposure ≥ 1 year to tenofovir] and [emtricitabine] were associated with a lower risk. The study provides valuable insights into the potential [metabolic side effects] of [ARVs] and highlights the need for close monitoring of [glucose levels] in [HIV-infected patients] receiving [ARV treatment].

Navigating the Metabolic Landscape of HIV Treatment

The study's findings emphasize the importance of considering the [metabolic effects] of [ARVs] in [HIV-infected patients]. Close monitoring of [glucose levels] and a proactive approach to [diabetes prevention] are essential for optimizing patient outcomes.

Living with HIV: A Holistic Approach to Care

The management of [HIV infection] requires a [holistic approach], encompassing both [viral suppression] and [prevention and management of co-morbidities] such as [diabetes]. A healthy lifestyle, including [regular exercise, a balanced diet, and maintaining a healthy weight], can significantly reduce the risk of [metabolic complications] associated with [HIV treatment].

Dr.Camel's Conclusion

This study underscores the importance of personalized care in the management of [HIV infection]. Like a wise desert guide, clinicians must carefully consider the potential [side effects] of [ARVs] and tailor treatment strategies to each individual's needs. This research highlights the ongoing quest for more effective and safer treatments for [HIV], ensuring a brighter future for individuals living with this condition.

Date :
  1. Date Completed 2015-09-11
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

25886928

DOI: Digital Object Identifier

10.1097/QAI.0000000000000647

Related Literature

Article Analysis
・Effects of didanosine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.