Methylnaltrexone for Opioid-Induced Constipation in Children and Adolescents and Young Adults with Progressive Incurable Cancer at the End of Life.

Author: BakerJustin N, FlerlageJamie E

Paper Details 
Original Abstract of the Article :
Opioid-induced constipation (OIC) is common among children and adolescents and young adults (AYA) with progressive incurable cancer. Although methylnaltrexone is a successful treatment for OIC in adult cancer patients, no case series has established its safety and efficacy in pediatric cancer patien...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492591/

データ提供:米国国立医学図書館(NLM)

Methylnaltrexone: A New Oasis for Opioid-Induced Constipation

The journey of progressive incurable cancer can be a difficult one, often marked by debilitating side effects, including opioid-induced constipation (OIC). This study investigates the potential of methylnaltrexone, a medication already used in adults, for treating OIC in children and adolescents with cancer. The study notes that while methylnaltrexone has proven successful in adults, there's a lack of research on its use in pediatric cancer patients. This highlights the need for more studies to ensure the safety and efficacy of this medication for this vulnerable population.

A Path to Relief for Young Patients

This study emphasizes the need for more research to establish the safety and efficacy of methylnaltrexone for treating OIC in children and adolescents with cancer. This is crucial for ensuring that young patients have access to effective treatments and can navigate the challenging terrain of their illness with as much comfort as possible.

Navigating the Challenges of Pediatric Cancer

Opioid-induced constipation can significantly impact the quality of life for children and adolescents with cancer. Finding effective and safe treatments for this side effect is essential for supporting these young patients through their journey.

Dr.Camel's Conclusion

This study highlights the urgent need for more research into the use of methylnaltrexone for treating OIC in pediatric cancer patients. Providing effective and safe treatment options for these young patients is crucial for improving their well-being and ensuring they receive the best possible care as they navigate the challenging desert of their illness.
Date :
  1. Date Completed 2016-04-11
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

25927665

DOI: Digital Object Identifier

PMC4492591

Related Literature

SNS
PICO Info
in preparation
Languages

English

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