Paper Details

  1. Home
  2. Paper Details

Effective delivery of apomorphine in the management of Parkinson disease: practical considerations for clinicians and Parkinson nurses.

Author: BhidayasiriRoongroj, BoonpangKamolwan, ChaudhuriK Ray, LeWittPeter, MartinAnne, van LaarTeus

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Apomorphine, a dopamine agonist, is a subcutaneous treatment for Parkinson's disease (PD) that can be used to manage 'off' periods and motor fluctuations. This article discusses the benefits and risks of apomorphine use.
Paper Details　
Original Abstract of the Article :
The clinical utility of long-term oral levodopa therapy in Parkinson disease (PD) is often limited by the emergence of motor complications. Over time, many patients with PD experience regular and/or unpredictable "off" periods, despite taking optimized oral medication regimens, with a major negative...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/25970277

データ提供：米国国立医学図書館（NLM）

Apomorphine: A Vital Tool in Managing Parkinson's Disease

Long-term oral levodopa therapy is often used to manage Parkinson's disease (PD), but motor complications can arise over time. This review examines the efficacy of subcutaneous apomorphine administration, a dopaminergic agonist, in addressing these motor fluctuations and improving quality of life for PD patients.

Apomorphine: A Promising Treatment for Motor Fluctuations

The review highlights the potential of apomorphine for treating patients experiencing 'off' periods and managing motor fluctuations refractory to conventional oral therapy. The authors discuss three primary approaches to apomorphine administration: intermittent injection, continuous infusion, and the apomorphine response test. They emphasize the importance of a multidisciplinary team, including specialist nurses, in managing PD patients and optimizing apomorphine therapy.

The Importance of Multidisciplinary Care in Parkinson's Disease

Imagine a camel caravan traversing a challenging desert landscape, each member playing a vital role in ensuring the group's survival and well-being. Similarly, managing PD effectively requires a multidisciplinary team approach, involving physicians, nurses, physical therapists, and other healthcare professionals. This review highlights the crucial role of a collaborative team in optimizing apomorphine therapy and improving the quality of life for PD patients.

Dr. Camel's Conclusion

This review highlights the efficacy of apomorphine in managing motor fluctuations in Parkinson's disease, emphasizing the importance of a multidisciplinary team approach to optimize treatment and improve patient outcomes. As we continue to explore the complexities of neurodegenerative diseases, we must embrace a collaborative and holistic approach to patient care, seeking innovative strategies to enhance quality of life and promote well-being for those affected.
Date :
  1. Date Completed 2016-04-07
  2. Date Revised 2015-05-14
Further Info :

Pubmed ID

25970277

DOI: Digital Object Identifier

00002826-201505000-00003

Related Literature

Article Analysis
・Effects of apomorphine injection
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.