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Effects of 3,5-Diiodotyrosine and Potassium Iodide on Thyroid Function and Oxidative Stress in Iodine-Excess Wistar Rats.

Author: BaoWei, ChenHongxia, LinXinying, LiuDan, WangXia, YuFugui, ZhangMan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study compared the effects of organic iodine (3,5-diiodotyrosine, DIT) and inorganic iodine (potassium iodine, KI) on thyroid function and oxidative stress in rats. The study found that DIT had a less damaging effect on thyroid follicular cells than KI when exposed to supraphysiological iodine. DIT also balanced the antioxidant system, suggesting that it may be a safer alternative to KI in iodized salt.
Paper Details　
Original Abstract of the Article :
The objective of this study was to investigate the effects of organic iodine (3,5-diiodotyrosine, DIT) and inorganic iodine (potassium iodine, KI) on thyroid function and oxidative stress in iodine-excess Wistar rats. Seventy-two Wistar rats were randomly divided into eight groups: normal control (N...See full text at original site
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引用元：
https://doi.org/10.1007/s12011-015-0371-y

データ提供：米国国立医学図書館（NLM）

The Effects of Iodine on Thyroid Function and Oxidative Stress

The thyroid gland, like a delicate desert flower, is sensitive to environmental changes. This research investigates the effects of organic and inorganic iodine on thyroid function and oxidative stress in rats. The study compares the impact of 3,5-diiodotyrosine (DIT) and potassium iodide (KI) on thyroid health. It's like examining the impact of different water sources on the growth and resilience of a desert garden.

Iodine: A Balancing Act in the Desert of Thyroid Health

The study revealed that DIT, compared to KI, had a more protective effect on thyroid function and oxidative stress. It's like observing how different watering techniques can impact the health of a desert garden – some methods might lead to overgrowth, while others promote balanced growth and resilience.

Navigating Iodine Supplementation

This research suggests that DIT might be a safer alternative to KI as a source of iodine in iodized salt. It's like finding a more sustainable source of water for the desert garden, minimizing the risk of oversaturation and promoting healthy growth.

Dr.Camel's Conclusion

This study highlights the intricate relationship between iodine and thyroid health. It's like a desert explorer discovering that different types of water sources have varying effects on the delicate balance of the desert ecosystem. The research emphasizes the need for a balanced approach to iodine supplementation, ensuring that we're not simply pouring water into the desert, but providing the right kind of nourishment to support healthy growth.

Date :
  1. Date Completed 2016-10-12
  2. Date Revised 2016-12-30
Further Info :

Pubmed ID

26002813

DOI: Digital Object Identifier

10.1007/s12011-015-0371-y

Related Literature

Article Analysis
・Effects of potassium iodide
SNS
PICO Info
in preparation
Languages

English

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