Post-marketing monitoring of intussusception after rotavirus vaccination in Japan.

Author: BauchauVincent, BuyseHubert, HollKatsiaryna, MahauxOlivia, SugiyamaKeiji, Van HolleLionel

Paper Details 
Original Abstract of the Article :
PURPOSE: Rotarix(TM) was launched in November 2011 in Japan to prevent rotavirus gastroenteritis. Some studies suggest that Rotarix(TM) may have a temporal association with a risk of intussusception (IS). We assessed a possible association between IS and Rotarix(TM) vaccination in Japan. METHODS: A...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736691/

データ提供:米国国立医学図書館(NLM)

Rotavirus Vaccination and Intussusception: A Closer Look at Post-Marketing Surveillance

The implementation of [rotavirus vaccination] has been a significant milestone in public health, like a life-saving oasis in a desert ravaged by disease. However, as with any new intervention, [safety surveillance] is crucial. This research explores the potential association between [rotavirus vaccination] and [intussusception], utilizing [post-marketing monitoring data] to assess the risk. The authors analyze [observed versus expected cases] of [intussusception] in [Japan] following the introduction of [Rotarix(TM)]. Their findings provide insights into the potential risks and benefits of [rotavirus vaccination].

Rotavirus Vaccination: Weighing the Benefits and Risks

The authors find a [statistically significant excess] of [intussusception] cases within [7 days] following the [first dose] of [Rotarix(TM)]. However, they observe no such association with the [second dose]. It's like navigating a desert with potential hazards along the way. While the benefits of [rotavirus vaccination] are undeniable, it's important to be aware of the [potential risks]. This research underscores the importance of [ongoing post-marketing surveillance] to ensure the safety and effectiveness of [vaccines].

Vaccination Decisions: A Balancing Act Between Risks and Benefits

The authors' findings highlight the need for [informed decision-making] regarding [vaccination]. It's important to [weigh the potential benefits and risks] of any vaccine, considering your individual circumstances and discussing your concerns with a [healthcare professional]. Remember, vaccination is one of the most effective ways to protect yourself and your loved ones from [preventable diseases]. However, it's important to be aware of the potential side effects and discuss them with your doctor.

Dr.Camel's Conclusion

This research is a reminder that the journey through [vaccine development and implementation] is not without its challenges. While [rotavirus vaccination] has been a tremendous success, it's important to remain vigilant about potential risks and continue to monitor the safety of this crucial public health intervention. It's like building a safe haven in the desert, ensuring that the benefits outweigh the risks and that everyone has access to safe and effective vaccines.

Date :
  1. Date Completed 2016-03-31
  2. Date Revised 2021-01-09
Further Info :

Pubmed ID

26013569

DOI: Digital Object Identifier

PMC4736691

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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