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Acute effects of riociguat in borderline or manifest pulmonary hypertension associated with chronic obstructive pulmonary disease.
Author: BehrJuergen, FreyReiner, GhofraniHossein A, GrimmingerFriedrich, GrünigEkkehard, HalankMichael, MitrovicVeselin, MueckWolfgang, SchermulyRalph T, StaehlerGerd, UngerSigrun
Original Abstract of the Article :
Riociguat is the first oral soluble guanylate cyclase stimulator shown to improve pulmonary hemodynamics in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension (PH). This pilot study assessed the impact of a single dose of riociguat on hemodynamics, gas ex...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449240/
データ提供:米国国立医学図書館(NLM)
Riociguat: A Promising Hope for Pulmonary Hypertension?
Pulmonary hypertension, a condition that affects the blood vessels in the lungs, can be a challenging diagnosis. This study investigates the potential of riociguat, a new drug that stimulates soluble guanylate cyclase, to improve pulmonary hemodynamics in patients with pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD). It's like a camel seeking a fresh water source in a parched desert, hoping to find relief from a debilitating condition.
A Desert of Hope: Riociguat Shows Promise
This study shows that riociguat was well-tolerated and led to significant improvements in pulmonary hemodynamics in patients with COPD-associated pulmonary hypertension. This suggests that riociguat could offer a new and effective treatment option for these patients, like discovering a hidden oasis in the desert. However, larger and longer-term studies are still needed to confirm these findings.
A Journey to Health: More Research Needed
The study calls for further research to evaluate the long-term effects of riociguat in patients with COPD-associated pulmonary hypertension. This is like carefully mapping out a long journey through the desert to ensure a safe and successful trek. While the initial findings are promising, more research is needed to fully understand the benefits and risks of this new drug.
Dr. Camel's Conclusion
This study offers a glimmer of hope for patients struggling with pulmonary hypertension. Riociguat shows promise as a potential treatment option, but further research is needed to confirm its long-term efficacy and safety. Like a camel seeking a safe haven in the vast desert, we must continue our journey to find effective treatments for all.
Date :
- Date Completed 2015-06-11
- Date Revised 2020-09-30
Further Info :
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