[In what extend we can reach the current LDL-cholesterol treatment goals in secondary prevention].

Author: , BruthansJan, MayerOtto

Paper Details 
Original Abstract of the Article :
BACKGROUND: A number of clinical trials have shown that patients with overt atherovascular disease may benefit from more aggressive dosage of statins. We aimed to determined the usual dosage of statin in clinical practice and the adherence to recommended target concentration of LDL-cholesterol. MET...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/26075853

データ提供:米国国立医学図書館(NLM)

Statin Use in Secondary Prevention of CHD

The field of cardiology is constantly evolving, with new guidelines and treatment strategies emerging to improve patient outcomes. This research delves into a critical challenge in secondary prevention of coronary heart disease (CHD): achieving optimal LDL-cholesterol levels. The study employed a retrospective analysis of a large cohort of patients with a history of acute coronary syndrome and/or coronary revascularization. The researchers aimed to determine the typical dosage of statins in clinical practice and assess adherence to recommended LDL-cholesterol targets. They discovered that while a substantial majority of CHD patients were on statins, the prescribed dosages and adherence to target values often fell short of current therapeutic standards.

Adherence to LDL-Cholesterol Targets

The findings revealed that only a small percentage of patients were receiving the highest dose of statins, even though guidelines recommend aggressive treatment for those with overt atherovascular disease. Additionally, while there was some improvement in adherence to older LDL-cholesterol targets, the more recent, stricter target was met in less than 25% of patients. The study's analysis suggests that even with maximum statin up-titration, achieving the current LDL-cholesterol target might be a challenge for many patients.

Optimizing Statin Therapy

This research highlights the need for a closer look at statin prescribing practices and patient adherence in secondary prevention of CHD. It underscores the importance of patient education, medication monitoring, and personalized treatment approaches to optimize statin therapy and improve patient outcomes. We can strive for greater adherence to therapeutic guidelines, achieving better control of LDL-cholesterol levels, and ultimately improving the health and well-being of CHD patients.

Dr.Camel's Conclusion

This research is like a compass, guiding us towards a deeper understanding of statin therapy in CHD prevention. We need to ensure that patients are receiving the appropriate statin dose and support their adherence to treatment. This journey towards better heart health will require collaboration between healthcare providers, patients, and researchers.

Date :
  1. Date Completed 2015-10-26
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26075853

DOI: Digital Object Identifier

52337

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PICO Info
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Languages

Czech

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