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Appropriateness of oral drugs for long-term treatment of lower urinary tract symptoms in older persons: results of a systematic literature review and international consensus validation process (LUTS-FORTA 2014).

Author: BecherKlaus, Castro-DiazDavid, Chartier-KastlerEmmanuel, KirbyMike, OelkeMatthias, WaggAdrian, WehlingMartin

Consensus Development ConferenceA conference organized by the National Institutes of Health (NIH) to develop consensus and recommendations on medical issues.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Dutasteride, fesoterodine, and finasteride were classified as beneficial for older persons. The use of most other drugs for LUTS in older persons is questionable or should be avoided.
Paper Details　
Original Abstract of the Article :
AIM: we aimed to systematically review drugs to treat lower urinary tract symptoms (LUTS) regularly used in older persons to classify appropriate and inappropriate drugs based on efficacy, safety and tolerability by using the Fit fOR The Aged (FORTA) classification. METHODS: to evaluate the efficac...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615806/

データ提供：米国国立医学図書館（NLM）

Navigating the Desert of Lower Urinary Tract Symptoms in Older Adults: A Guide to Drug Treatment

Lower urinary tract symptoms (LUTS) are common in older adults, potentially impacting their quality of life. This study systematically reviews the available drugs for treating LUTS in older adults, focusing on their efficacy, safety, and tolerability. The study's findings, like a carefully curated oasis in the desert of LUTS, identify three drugs as beneficial for older adults: dutasteride, fesoterodine, and finasteride. The study also highlights the limited evidence supporting the use of many other drugs for LUTS in older adults, emphasizing the need for caution and individualized treatment approaches.

Dutasteride, Fesoterodine, and Finasteride: Oases in the Desert of LUTS

The study identified dutasteride, fesoterodine, and finasteride as the only drugs that emerged as beneficial for treating LUTS in older adults. These drugs, like oases in the vast desert of LUTS, offer potential relief and improved quality of life for older adults struggling with these symptoms.

Navigating the Desert of LUTS with Caution: A Guide for Older Adults

This study underscores the importance of careful consideration when choosing medications for LUTS in older adults. The study's findings highlight the need for further research to establish the efficacy and safety of many drugs commonly used for LUTS in this population. It's essential to consult with a healthcare professional to discuss individual needs and potential risks before starting any medication for LUTS. This approach can help older adults navigate the desert of LUTS with greater awareness and safety.

Dr.Camel's Conclusion

This study provides valuable insights into the use of drugs for LUTS in older adults, emphasizing the need for careful consideration and individualized treatment approaches. The study's findings highlight the limited evidence supporting many drugs commonly used for LUTS in this population, emphasizing the need for further research to establish their efficacy and safety. This study serves as a guide for clinicians and patients in navigating the desert of LUTS with greater knowledge and awareness.

Date :
  1. Date Completed 2016-06-07
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

26104505

DOI: Digital Object Identifier

PMC4615806

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