Adverse events associated with somatostatin analogs in acromegaly.

Author: AuriemmaRenata S, ColaoAnnamaria, GrassoLudovica F S, PivonelloRosario

Paper Details 
Original Abstract of the Article :
In patients with acromegaly, somatostatin analogs (SSA) represent the first choice medical treatment. The long-acting SSA have been found to be effective in controlling growth hormone and IGF-I levels in a high percentage of patients, resulting in an improvement in the quality of life; moreover, the...See full text at original site
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引用元:
https://doi.org/10.1517/14740338.2015.1059817

データ提供:米国国立医学図書館(NLM)

Somatostatin Analogs in Acromegaly: A Tale of Two Sides

Acromegaly, a condition caused by excessive growth hormone production, can lead to a range of physical and metabolic complications. This review explores the role of somatostatin analogs (SSAs) in the treatment of acromegaly, highlighting their effectiveness in controlling growth hormone and IGF-I levels while providing a proven safety record. The authors discuss the benefits of long-acting SSAs, emphasizing their ability to improve the quality of life for patients with acromegaly. However, they also acknowledge that SSAs can be associated with certain adverse events, including gastrointestinal side effects, gallstones, and hypoglycemia.

A Desert Oasis of Treatment: Navigating the Complexities of Acromegaly

Imagine a traveler traversing a vast desert, seeking a respite from the harsh conditions. The discovery of an oasis brings relief and sustenance, but it also presents new challenges, such as the need to navigate the surrounding terrain and manage the resources available. Similarly, SSAs offer a valuable oasis for patients with acromegaly, providing effective treatment but also requiring careful monitoring and management of potential side effects.

Balancing the Benefits and Risks: A Journey of Careful Management

This research underscores the importance of balancing the benefits and risks associated with SSA treatment for acromegaly. While these drugs offer effective control of growth hormone and IGF-I levels, patients and healthcare providers must be vigilant in monitoring for potential side effects. A personalized approach, considering individual patient needs and characteristics, is crucial for navigating the therapeutic landscape and ensuring optimal patient outcomes.

Dr.Camel's Conclusion

This review provides a comprehensive overview of the role of somatostatin analogs in the treatment of acromegaly. While SSAs offer a promising therapeutic option, careful monitoring for potential side effects and a personalized approach to treatment are essential for maximizing patient well-being and achieving optimal outcomes.

Date :
  1. Date Completed 2016-03-21
  2. Date Revised 2015-07-18
Further Info :

Pubmed ID

26184380

DOI: Digital Object Identifier

10.1517/14740338.2015.1059817

Related Literature

SNS
PICO Info
in preparation
Languages

English

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