Postmarketing Safety Profile of Subcutaneous Interferon Beta-1a Given 3 Times Weekly: A Retrospective Administrative Claims Analysis.

Author: CorvinoFrank A, GuedesSandra, RichyFlorent F, Sabidó-EspinMeritxell, SamuelsonMark, SmithMeredith Y, TrochanovAnton

Paper Details 
Original Abstract of the Article :
Health insurance administrative claims databases represent a valuable source of information regarding the safety profile of marketed products as used in actual clinical practice in a broader range of patients than that assessed in clinical trials. Interferon beta-1a administered subcutaneously 3 tim...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398224/

データ提供:米国国立医学図書館(NLM)

A Real-World Oasis: Exploring Interferon Beta-1a's Safety

The treatment of multiple sclerosis (MS) has significantly improved with the advent of disease-modifying therapies, such as interferon beta-1a. This research explores the safety profile of interferon beta-1a administered subcutaneously three times weekly, a treatment approved for relapsing-remitting MS. The study leverages a real-world evidence source—health insurance administrative claims databases—to provide insights into the safety profile of interferon beta-1a as used in actual clinical practice.

Navigating the Sands of Safety Data

The study's findings provide valuable information regarding the safety profile of interferon beta-1a in a broader patient population than those included in clinical trials. While the study does not provide specific details about adverse events, it highlights the importance of real-world data in understanding the long-term safety of medications.

A Desert Oasis of Knowledge: Understanding Medication Safety

Imagine a desert traveler relying on a map to navigate the vast landscape. Real-world evidence, like the data collected from insurance claims databases, provides a more comprehensive view of the safety profile of medications, just as a detailed map helps a traveler understand the terrain. This research emphasizes the importance of real-world data in complementing clinical trial findings, providing a more complete picture of medication safety and effectiveness.

Dr.Camel's Conclusion

This research emphasizes the value of real-world evidence in understanding the safety profile of medications like interferon beta-1a. By leveraging health insurance administrative claims databases, researchers can gain insights into the long-term safety of medications as used in actual clinical practice, supplementing the information gathered from clinical trials.

Date :
  1. Date Completed 2016-05-05
  2. Date Revised 2023-08-05
Further Info :

Pubmed ID

26233537

DOI: Digital Object Identifier

PMC10398224

SNS
PICO Info
in preparation
Languages

English

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