Do labetalol and methyldopa have different effects on pregnancy outcome? Analysis of data from the Control of Hypertension In Pregnancy Study (CHIPS) trial.

Author: , AsztalosE, GafniA, GanzevoortJ W, GruslinA, HelewaM, HuttonE, KorenG, LeeS K, LeeT, LoganA G, MageeL A, MenziesJ, MoutquinJ-M, MurphyK E, ReyE, RossS, SanchezJ, SingerJ, ThorntonJ G, WelchR, von DadelszenP

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To compare pregnancy outcomes, accounting for allocated group, between methyldopa-treated and labetalol-treated women in the CHIPS Trial (ISRCTN 71416914) of 'less tight' versus 'tight' control of pregnancy hypertension. DESIGN: Secondary analysis of CHIPS Trial cohort. SETTING: Interna...See full text at original site
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引用元:
https://doi.org/10.1111/1471-0528.13569

データ提供:米国国立医学図書館(NLM)

Comparing the Impact of Labetalol and Methyldopa on Pregnancy Outcomes

This secondary analysis, like a meticulous scientist comparing two different desert plants, examines the pregnancy outcomes of women treated with either labetalol or methyldopa in the Control of Hypertension In Pregnancy Study (CHIPS). The researchers, much like explorers charting different paths through a desert landscape, seek to understand the relative impact of these two antihypertensive medications on the course of pregnancy.

Methyldopa: A Potential Advantage in Pregnancy Outcomes

The analysis suggests that [methyldopa treatment] may be associated with improved pregnancy outcomes compared to labetalol, particularly in women with pre-existing hypertension. These findings, like a hidden oasis offering a respite from the harsh desert conditions, provide valuable insights into the potential benefits of methyldopa for managing pregnancy hypertension.

Implications for Pregnancy Management

This study has important implications for the management of [pregnancy hypertension]. The findings highlight the potential benefits of methyldopa and suggest that it may be a preferable treatment option for certain groups of pregnant women. This information can guide clinicians in making more informed decisions regarding the best course of treatment for their patients.

Dr.Camel's Conclusion

This study, much like a camel guiding a caravan through the desert, provides valuable insights into the complex world of pregnancy hypertension. The findings suggest that methyldopa may offer advantages in terms of pregnancy outcomes, offering a potential path towards a smoother and more successful journey for both mother and child.

Date :
  1. Date Completed 2018-07-30
  2. Date Revised 2018-07-30
Further Info :

Pubmed ID

26265372

DOI: Digital Object Identifier

10.1111/1471-0528.13569

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English

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