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A 4-week pilot study with the cannabinoid receptor agonist dronabinol and its effect on metabolic parameters in a randomized trial.

Author: BaymanLevent, ReichenbachZachary Wilmer, Rizvi-TonerAmna, ScheyRon, SloanJoshua, ValestinJessica

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Dronabinol, a synthetic Δ(9)-tetrahydrocannabinol, has been used to treat nausea and vomiting from chemotherapy, stimulate appetite in AIDS patients, and treat noncardiac chest pain. This study explores its long-term effects on metabolic parameters.
Paper Details　
Original Abstract of the Article :
Dronabinol (synthetic Δ(9)- tetrahydrocannabinol) is used in patients with nausea and vomiting from chemotherapy and in AIDS patients for appetite stimulation. Recently, dronabinol was used to successfully treat visceral hypersensitivity causing noncardiac chest pain. With widening uses of this medi...See full text at original site
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引用元：
https://doi.org/10.1016/j.clinthera.2015.07.023

データ提供：米国国立医学図書館（NLM）

Dronabinol's Effects on Metabolic Parameters: A Pilot Study

Dronabinol, a synthetic cannabinoid, is used to treat various conditions, but its potential effects on metabolism are still being explored. This pilot study investigates the impact of dronabinol on metabolic parameters in a randomized trial, aiming to determine whether long-term use of dronabinol significantly affects metabolic health. Researchers examine the effects of dronabinol on various metabolic markers, including glucose, lipids, and hormones.

Dronabinol's Potential Impact on Metabolism

This pilot study suggests that dronabinol, while effective in treating certain conditions, may have some metabolic effects. The authors found that long-term use of dronabinol was associated with changes in some metabolic parameters, though these changes were not considered clinically significant. This research provides preliminary data that can be used to further investigate the potential metabolic effects of dronabinol. Just as a desert traveler must carefully monitor their water intake, healthcare professionals may need to consider the potential metabolic effects of dronabinol in patients who use it long-term.

Understanding the Long-Term Effects of Medications

This pilot study highlights the importance of ongoing research to understand the long-term effects of medications, particularly those with potential metabolic implications. It emphasizes the need for continued monitoring and research to ensure that patients receive the safest and most effective treatments. Just as a desert explorer must be aware of the long-term effects of the harsh environment on their body, healthcare professionals must be vigilant in understanding the long-term effects of medications on patients.

Dr.Camel's Conclusion

This pilot study provides preliminary data on the metabolic effects of dronabinol. It underscores the importance of continued research to understand the long-term effects of medications, particularly those that may have metabolic implications. This research is a reminder that we must remain vigilant in our pursuit of safe and effective treatments for patients.
Date :
  1. Date Completed 2016-05-17
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26283236

DOI: Digital Object Identifier

10.1016/j.clinthera.2015.07.023

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・Effects of dronabinol
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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