Suvorexant for Primary Insomnia: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.

Author: IwataNakao, KishiTaro, MatsunagaShinji

Paper Details 
Original Abstract of the Article :
OBJECTIVE: We performed a systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials evaluating suvorexant for primary insomnia. METHODS: Relevant studies were identified through searches of PubMed, databases of the Cochrane Library, and PsycINFO citations through Ju...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4552781/

データ提供:米国国立医学図書館(NLM)

Suvorexant: A Beacon of Hope for Primary Insomnia

Sleep, a vital pillar of well-being, is often elusive for those struggling with insomnia. This systematic review and meta-analysis embarked on a journey to assess the efficacy and safety of suvorexant in treating primary insomnia. The researchers, akin to astronomers meticulously charting the celestial bodies, meticulously gathered data from four randomized, placebo-controlled trials involving over 3,000 patients. Their findings, like a shimmering oasis in the vast desert of insomnia, revealed suvorexant's superiority in improving both subjective total sleep time and subjective time-to-sleep onset compared to a placebo. While suvorexant did increase the incidence of certain side effects, it did not significantly impact trial discontinuations, signifying its overall tolerability. This research offers valuable evidence for the potential of suvorexant in improving sleep quality for individuals battling primary insomnia.

Suvorexant: A Potential Remedy for Sleepless Nights

The results of this meta-analysis paint a hopeful picture for those struggling with primary insomnia. Suvorexant demonstrates significant improvement in sleep parameters, offering a glimmer of hope for a good night's rest. While the presence of side effects requires careful monitoring, the overall tolerability of suvorexant is encouraging. This research highlights the potential of pharmacological interventions in addressing insomnia.

Sleeping Soundly: Tips for a Restful Night

Finding a solution for insomnia can feel like traversing a vast, dusty desert. This research offers a potential oasis in the form of suvorexant. Remember, maintaining a consistent sleep schedule, creating a relaxing bedtime routine, and avoiding stimulants before bed can also contribute to improved sleep quality. Consult a healthcare professional to determine the most suitable treatment for your individual needs.

Dr.Camel's Conclusion

This meta-analysis suggests that suvorexant holds promise as an effective treatment for primary insomnia. While side effects are a consideration, the overall tolerability and improvement in sleep parameters make it a potential option for those seeking a restful night's sleep.
Date :
  1. Date Completed 2016-05-24
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

26317363

DOI: Digital Object Identifier

PMC4552781

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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