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Antipsychotic medications for the treatment of delirium: a systematic review and meta-analysis of randomised controlled trials.

Author: HirotaTomoya, IwataNakao, KishiTaro, MatsunagaShinji

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Second-generation antipsychotics (SGAs) were more beneficial than haloperidol in treating delirium, with regard to both efficacy and safety. However, further research with larger samples is needed.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: We performed an updated meta-analysis of antipsychotic treatment in patients with delirium, based on a previous meta-analysis published in 2007. METHODS: Included in this study were randomised, placebo-controlled or usual care (UC) controlled trials of antipsychotics in adult patients w...See full text at original site
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引用元：
https://doi.org/10.1136/jnnp-2015-311049

データ提供：米国国立医学図書館（NLM）

Navigating the Delirium Landscape: Antipsychotic Medications

Delirium, a state of altered consciousness, can be a challenging and frightening experience, like getting lost in a vast and unfamiliar desert. This study, like a group of researchers seeking a safe passage through this mental landscape, explores the use of antipsychotic medications for treating delirium. The authors conducted a meta-analysis of randomized controlled trials to evaluate the effectiveness and safety of antipsychotic medications in this context.

Second-Generation Antipsychotics: A Potential Oasis

The study's findings, like a shimmering oasis in the desert, suggest that second-generation antipsychotics (SGAs) may offer a more favorable approach to treating delirium compared to haloperidol. SGAs were associated with shorter time to response and a lower incidence of extrapyramidal symptoms, offering potential advantages in terms of both efficacy and safety.

Guiding Principles for Treating Delirium

This study, like a well-equipped caravan navigating a challenging terrain, offers valuable insights for clinicians seeking to treat delirium. The findings suggest that SGAs, like a refreshing spring in the desert, may provide a more effective and safer approach compared to haloperidol. However, the authors acknowledge the need for further research, emphasizing the importance of continued exploration in this complex and evolving field.

Dr.Camel's Conclusion

This study, like a camel traversing the desert of mental health, sheds light on the potential of antipsychotic medications for treating delirium. The findings suggest that SGAs may offer a more favorable approach compared to haloperidol, providing a potential oasis in the desert of delirium treatment. As we continue to explore the vast landscape of mental health research, this study serves as a valuable guidepost, informing our understanding and treatment of this complex condition.

Date :
  1. Date Completed 2017-05-24
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

26341326

DOI: Digital Object Identifier

10.1136/jnnp-2015-311049

Related Literature

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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