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Effects of repeated asenapine in a battery of tests for anxiety-like behaviours in mice.

Author: BarakNoa, EinatHaim, EneHila M, KaraNirit Z, Reshef Ben-MordechaiTal

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Asenapine, a new atypical antipsychotic, has a broad pharmacological profile with significant effects on serotonergic receptors, suggesting potential anxiolytic effects. This study investigated the effects of asenapine on anxiety-like behavior in mice.
Paper Details　
Original Abstract of the Article :
A number of atypical antipsychotic drugs were demonstrated to have anxiolytic effects in patients and in animal models. These effects were mostly suggested to be the consequence of the drugs' affinity to the serotonin system and its receptors. Asenapine is a relatively new atypical antipsychotic tha...See full text at original site
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引用元：
https://doi.org/10.1017/neu.2015.53

データ提供：米国国立医学図書館（NLM）

Asenapine: A Promising Antipsychotic with Potential Anxiolytic Effects

The realm of mental health is a complex landscape, and researchers are constantly seeking new and effective treatments for conditions like anxiety and schizophrenia. This study explores the potential anxiolytic effects of asenapine, a relatively new atypical antipsychotic medication, in mice.

Atypical antipsychotics are known to affect the serotonin system in the brain, which plays a crucial role in regulating mood and anxiety. The researchers designed experiments to test the effects of asenapine on anxiety-like behaviors in mice, and their results were encouraging.

A Potential New Anxiolytic?

This research suggests that asenapine may possess anxiolytic properties, potentially opening up new therapeutic avenues for treating anxiety disorders. It's like discovering a hidden oasis in the vast desert of mental health research, offering a potential source of relief for those struggling with anxiety.

A New Hope for Anxiety Treatment

The findings suggest that asenapine could be a valuable addition to the arsenal of treatments for anxiety disorders. However, further research is needed to confirm these findings and evaluate the safety and efficacy of asenapine in humans. This could be a significant breakthrough in treating anxiety disorders and offering much-needed relief to individuals suffering from this debilitating condition.

Dr.Camel's Conclusion

This study offers a glimmer of hope in the fight against anxiety. Asenapine's potential anxiolytic effects, while still needing confirmation in humans, could lead to new and effective treatment options for individuals suffering from anxiety disorders. It's a reminder that the search for solutions in the vast desert of mental health research is ongoing, and discoveries are constantly emerging.

Date :
  1. Date Completed 2016-12-13
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

26357996

DOI: Digital Object Identifier

10.1017/neu.2015.53

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Article Analysis
・Effects of asenapine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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