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Novel glucocorticoids: where are we now and where do we want to go?

Author: BijlsmaJ W J, ButtgereitFrank, SpiesCornelia M

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Glucocorticoids (GCs) are effective treatments for many inflammatory conditions, but they can also cause side effects. This study explores new approaches to improve the benefit-to-risk ratio of GC therapy, including chronotherapeutic formulations, selective GC receptor agonists, and liposomal GCs.
Paper Details　
Original Abstract of the Article :
Glucocorticoid (GC) therapy is widely accepted as effective treatment for many inflammatory conditions. However, the potential of GC to produce adverse effects may prompt both patients and prescribing doctors to take a critical view on these important drugs. The increasing awareness of potential sid...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/26457359

データ提供：米国国立医学図書館（NLM）

Novel Glucocorticoids: Seeking a Balance in the Desert of Treatment

Glucocorticoids are powerful anti-inflammatory drugs, often used to treat various conditions. However, their potential side effects can be a challenge, much like navigating a treacherous desert terrain. This research explores ongoing efforts to optimize glucocorticoid therapy, focusing on improving the benefit-risk ratio. The study discusses various approaches, including chronotherapeutic formulations, selective glucocorticoid receptor agonists, and liposomal glucocorticoids. This research, like a guide through a complex desert landscape, aims to improve the safety and efficacy of glucocorticoid treatment.

Finding the Right Path in the Desert of Glucocorticoid Therapy

This study demonstrates the ongoing effort to find safe and effective ways to manage inflammatory conditions using glucocorticoids. These efforts, like navigating a vast desert landscape, aim to identify the most beneficial and safe therapeutic pathways for patients. The study highlights the importance of individualized treatment approaches and continued research to optimize glucocorticoid therapy.

Managing the Effects of Glucocorticoids

The potential side effects of glucocorticoids are a concern for both patients and healthcare providers. This study highlights the importance of careful monitoring and personalized treatment plans to minimize risks while maximizing benefits. It is important to consult with a healthcare professional to discuss treatment options and potential risks.

Dr.Camel's Conclusion

This study emphasizes the ongoing efforts to refine glucocorticoid therapy, finding a balance between effectiveness and safety. It highlights the importance of continued research to improve the treatment of inflammatory conditions while minimizing potential side effects.

Date :
  1. Date Completed 2015-12-16
  2. Date Revised 2017-01-12
Further Info :

Pubmed ID

26457359

DOI: Digital Object Identifier

9905

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English

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