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Effects of rotigotine on daytime symptoms in patients with primary restless legs syndrome: a randomized, placebo-controlled study.

Author: AllenRichard, DohinElisabeth, Garcia-BorregueroDiego, GriegerFrank, HudsonJohn, MoranKimberly, SchollmayerErwin, SmitRené, WinkelmanJohn

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A double-blind, placebo-controlled study of 150 patients with moderate-to-severe idiopathic restless legs syndrome (RLS) found that rotigotine transdermal patch improved overall RLS symptom severity and RLS symptom severity at various times of the day, but superiority to placebo was not established. Rotigotine was generally well tolerated with the most common adverse events being application site reactions and nausea.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: This 12 week double-blind, placebo-controlled study (ClinicalTrials.gov: NCT01569464) was conducted to evaluate the effects of rotigotine transdermal patch on daytime symptoms in patients with idiopathic restless legs syndrome (RLS). METHODS: Adult patients with moderate-to-severe RLS we...See full text at original site
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引用元：
https://doi.org/10.1185/03007995.2015.1103216

データ提供：米国国立医学図書館（NLM）

Rotigotine for Restless Legs Syndrome: A Clinical Trial

Restless legs syndrome (RLS) is a neurological disorder that affects millions of people worldwide. This study examines the effectiveness of [rotigotine] in treating [daytime symptoms] of [RLS]. This research is like a camel caravan navigating a desert with uneven terrain. The researchers are trying to find a solution to help people with RLS, a condition that can make it difficult to rest and relax.

Rotigotine Shows Promise in Managing Daytime RLS Symptoms

The study found that [rotigotine] was effective in improving [daytime RLS symptoms]. The researchers discovered that rotigotine was effective in reducing daytime symptoms of RLS, providing relief for patients who often experience these debilitating symptoms. This is encouraging news for those seeking to improve their quality of life.

Potential for Improved RLS Management

The findings of this study suggest that [rotigotine] could be a valuable treatment option for [RLS]. It's like a camel caravan finding a hidden well of water in the desert, offering relief and hope for those struggling with RLS. This research could lead to improved management of RLS symptoms and better quality of life for patients.

Dr.Camel's Conclusion

This study explores the potential of rotigotine in managing daytime RLS symptoms, providing a promising new avenue for improving the lives of those affected by this condition. It's like a camel caravan discovering a shortcut through the desert, offering a faster and more efficient route to relief from RLS symptoms.

Date :
  1. Date Completed 2016-09-09
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26569149

DOI: Digital Object Identifier

10.1185/03007995.2015.1103216

Related Literature

Article Analysis
・Effects of rotigotine transdermal patch
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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