Effects of levomilnacipran ER on fatigue symptoms associated with major depressive disorder.

Author: ChenChangzheng, FavaMaurizio, FreemanMarlene P, GommollCarl, GreenbergWilliam M, RuthAdam

Paper Details 
Original Abstract of the Article :
The aim of this study was to evaluate the effects of levomilnacipran extended-release (ER) on depression-related fatigue in adults with major depressive disorder. Post-hoc analyses of five phase III trials were carried out, with evaluation of fatigue symptoms based on score changes in four items: Mo...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736297/

データ提供:米国国立医学図書館(NLM)

Fighting Fatigue in the Desert of Depression

Major depressive disorder (MDD) is like a relentless desert storm, leaving individuals feeling drained and exhausted. This research, published in the field of psychiatry, explores the effectiveness of levomilnacipran extended-release (ER) in treating depression-related fatigue. The study analyzed data from five phase III trials, evaluating the impact of levomilnacipran ER on fatigue symptoms using specific scales like the Montgomery-Åsberg Depression Rating Scale (MADRS) and the Hamilton Depression Rating Scale (HAMD17). The results revealed that levomilnacipran ER significantly improved fatigue symptoms, leading to a greater reduction in fatigue severity and a higher rate of symptom remission compared to placebo.

A Ray of Hope in the Desert

The study findings suggest that levomilnacipran ER may be an effective treatment for depression-related fatigue. The significant improvements observed in fatigue symptoms, including lassitude, work/activities, retardation, and somatic symptoms, offer a beacon of hope for individuals struggling with this debilitating side effect of depression. It’s like finding a ray of sunlight piercing through the clouds in a desert storm, offering a glimmer of hope and a sense of renewed energy.

Navigating the Desert of Fatigue

If you are struggling with depression-related fatigue, this research offers a potential solution. Levomilnacipran ER may be an effective treatment option for managing these symptoms, allowing you to navigate the desert of fatigue and regain your vitality. Remember, seeking professional help is essential for managing depression and finding the right treatment for you. It’s like having a knowledgeable guide lead you through the desert, providing support and direction on your journey to recovery.

Dr. Camel's Conclusion

This research sheds light on the potential of levomilnacipran ER in alleviating the debilitating fatigue associated with MDD. The study’s findings offer a ray of hope for those struggling with this common symptom of depression, providing valuable insights into potential treatment options. This research is like discovering a hidden oasis in the desert, offering much-needed refreshment and a path towards improved well-being.

Date :
  1. Date Completed 2016-10-25
  2. Date Revised 2019-01-09
Further Info :

Pubmed ID

26584326

DOI: Digital Object Identifier

PMC4736297

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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