A Randomized Controlled Exploratory Pilot Study to Evaluate the Effect of Rotigotine Transdermal Patch on Parkinson's Disease-Associated Chronic Pain.

Author: AsgharnejadMahnaz, BauerLars, ChaudhuriK Ray, DohinElisabeth, NiliusSigrid, RascolOlivier, SurmannErwin, ZesiewiczTheresa

Paper Details 
Original Abstract of the Article :
Pain is a troublesome nonmotor symptom of Parkinson's disease (PD). This double-blind exploratory pilot study (NCT01744496) was the first to specifically investigate the effect of a dopamine agonist on PD-associated pain as primary outcome. Patients with advanced PD (ie, receiving levodopa) and at l...See full text at original site
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引用元:
https://doi.org/10.1002/jcph.678

データ提供:米国国立医学図書館(NLM)

Rotigotine: A Potential Pain Reliever for Parkinson's Disease?

Parkinson's disease (PD), a neurodegenerative disorder, often comes with debilitating nonmotor symptoms, including chronic pain. This research investigates the potential of rotigotine, a dopamine agonist, to alleviate PD-associated chronic pain. The study, a double-blind exploratory pilot study, involved patients with advanced PD experiencing chronic pain. Patients were randomly assigned to receive either rotigotine or placebo for 12 weeks.

Rotigotine: A Potential Hope for PD-Associated Chronic Pain

The study found that rotigotine appeared to improve pain severity in patients with PD-associated chronic pain, with a numerical improvement in pain scores compared to placebo. While the study was exploratory and requires further confirmation in larger-scale studies, the findings suggest that rotigotine may offer a potential therapeutic option for managing PD-associated chronic pain.

Managing PD-Associated Pain: Exploring Novel Approaches

This research provides a promising lead for exploring new approaches to managing PD-associated chronic pain. Rotigotine, a dopamine agonist already used for treating PD symptoms, may offer a potential therapeutic option for addressing this debilitating nonmotor symptom. However, further research is needed to confirm these findings and assess the long-term efficacy and safety of rotigotine for managing PD-associated pain. Remember, just as a camel adapts to the desert's changing conditions, we must remain open to exploring novel approaches for addressing complex health challenges.

Dr. Camel's Conclusion

This research offers a glimmer of hope for individuals with PD-associated chronic pain. Rotigotine, a dopamine agonist, may offer a potential therapeutic option for alleviating pain. However, further research is needed to confirm these findings and assess the long-term efficacy and safety of rotigotine for managing this debilitating symptom. Remember, just as a camel navigates the desert with resilience and adaptability, we must remain committed to exploring new avenues for treating complex medical conditions.

Date :
  1. Date Completed 2017-08-15
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

26626320

DOI: Digital Object Identifier

10.1002/jcph.678

Related Literature

SNS
PICO Info
in preparation
Languages

English

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