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Stroke neuroprotection revisited: Intra-arterial verapamil is profoundly neuroprotective in experimental acute ischemic stroke.
Author: AronIshi, BixGregory J, FraserJustin F, ManiskasMichael E, RobertsJill M
Original Abstract of the Article :
While clinical trials have now solidified the role of thrombectomy in emergent large vessel occlusive stroke, additional therapies are needed to optimize patient outcome. Using our previously described experimental ischemic stroke model for evaluating adjunctive intra-arterial drug therapy after ves...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821022/
データ提供:米国国立医学図書館(NLM)
Intra-Arterial Verapamil: A Potential Neuroprotective Adjunct to Thrombectomy
This research investigates the [potential neuroprotective effects of intra-arterial verapamil] in [experimental acute ischemic stroke]. The authors utilized a [well-established stroke model] to evaluate the impact of [verapamil administration] after [vessel recanalization]. Their findings demonstrate [significant neuroprotective effects of verapamil], including [reduced infarct volume, astrogliosis, and cellular apoptosis] alongside [increased neuronal survival and functional outcome]. This research highlights the [promising potential of intra-arterial verapamil] as a [therapeutic adjunct to thrombectomy] in treating ischemic stroke. A key takeaway from this study is the [safety and efficacy of intra-arterial verapamil administration], suggesting it could be a valuable addition to the treatment arsenal for ischemic stroke.
Intra-Arterial Verapamil: A Potential Neuroprotective Adjunct to Thrombectomy
This study provides a compelling case for further investigation into the use of intra-arterial verapamil as a neuroprotective therapy for ischemic stroke. The findings suggest that this approach could potentially improve patient outcomes and enhance the effectiveness of thrombectomy.
Intra-Arterial Verapamil: A Potential Neuroprotective Adjunct to Thrombectomy
This research underscores the importance of exploring innovative approaches to neuroprotection in ischemic stroke. It highlights the potential of intra-arterial verapamil as a safe and effective adjunct to thrombectomy, offering a promising avenue for improving treatment outcomes and minimizing neurological damage.
Dr.Camel's Conclusion
The desert, with its shifting sands and hidden currents, is a reminder of the unpredictable nature of stroke. This research, like a camel traversing the vast desert landscape, seeks to navigate the complex terrain of stroke recovery. It explores the potential of intra-arterial verapamil as a powerful tool for neuroprotection, offering a glimmer of hope for those seeking to restore function and reclaim their lives after a stroke.
Date :
- Date Completed 2016-08-10
- Date Revised 2018-11-13
Further Info :
Related Literature
English
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