Efficacy of intravaginal dehydroepiandrosterone (DHEA) on moderate to severe dyspareunia and vaginal dryness, symptoms of vulvovaginal atrophy, and of the genitourinary syndrome of menopause.

Author: , ArcherDavid F, BalserJohn, BeauregardAdam, CôtéIsabelle, FrenetteLouise, KoltunWilliam, LabrieFernand, LavoieLyne, MartelCéline, MontesinoMarlene, MoyneurÉrick, ParentJulie, PortmanDavid, VachonAndrée, VaillancourtMario, YoungDouglas

Paper Details 
Original Abstract of the Article :
OBJECTIVE: The aim of this study is to confirm the local beneficial effects of intravaginal dehydroepiandrosterone (DHEA, Prasterone) on moderate to severe dyspareunia or pain at sexual activity, the most frequent symptom of vulvovaginal atrophy due to menopause or genitourinary syndrome of menopaus...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1097/GME.0000000000000571

データ提供:米国国立医学図書館(NLM)

The Quest for Oasis: Exploring the Effectiveness of Intravaginal DHEA for Menopausal Symptoms

The world of women's health, my dear friends, is a vast desert filled with challenges and triumphs. One such challenge, especially for women navigating the menopausal journey, is vulvovaginal atrophy, which can lead to discomforting symptoms like dyspareunia (pain during intercourse) and vaginal dryness. This research delves into the potential oasis of intravaginal dehydroepiandrosterone (DHEA), a naturally occurring hormone, as a treatment for these symptoms.

This study, a well-structured phase III clinical trial, examined the impact of daily intravaginal DHEA on women experiencing moderate to severe dyspareunia. The researchers meticulously monitored key indicators of vaginal health, including the percentage of parabasal and superficial cells, vaginal pH, and the severity of pain during intercourse. The results were quite promising!

A Beacon of Hope in the Desert of Menopause

The study revealed that intravaginal DHEA significantly improved the targeted symptoms. After 12 weeks of treatment, participants showed a significant decrease in parabasal cells, an increase in superficial cells, a reduction in vaginal pH, and a remarkable decline in the severity of dyspareunia compared to the placebo group. These findings suggest that DHEA could potentially be a valuable tool for alleviating the discomforts associated with vulvovaginal atrophy.

Navigating the Oasis of Women's Health: A Guide for Everyday Life

The results of this study offer a glimmer of hope for women experiencing the challenges of menopause. While it is crucial to remember that every woman's journey is unique, it is important to discuss these findings with your healthcare provider. They can help you determine if intravaginal DHEA might be a suitable option for you.

Dr. Camel's Conclusion

This research, like a refreshing oasis in the desert, offers a potential solution for the discomforts of vulvovaginal atrophy. The study's findings highlight the potential benefits of intravaginal DHEA as a treatment option for women experiencing these symptoms. Remember, my dear friends, navigating the desert of women's health requires an understanding of the terrain and the resources available. Consulting with a healthcare professional is essential for making informed decisions about your health and well-being.

Date :
  1. Date Completed 2016-12-13
  2. Date Revised 2022-07-26
Further Info :

Pubmed ID

26731686

DOI: Digital Object Identifier

10.1097/GME.0000000000000571

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.