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Preventive and Therapeutic Effects of the Retinoid X Receptor Agonist Bexarotene on Tumors.

Author: CaoXiaorong, GuoYuanyuan, LuanYuxia, QiLisi, ZhangPei

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Bexarotene is a promising anti-cancer agent that selectively activates retinoid X receptors, showing therapeutic effects on various tumors. Clinical studies have demonstrated its favorable therapeutic profile with mild side effects, particularly in combination with other therapies.
Paper Details　
Original Abstract of the Article :
We present a review of recent investigations of anticancer drug bexarotene in this article. As one of the novel synthetic analogs of retinoids, bexarotene selectively binds to and activates the retinoid X receptor (RXRs) subfamilies, exerting a prophylactic and therapeutic effect on a large series o...See full text at original site
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引用元：
https://doi.org/10.2174/138920021702160114121706

データ提供：米国国立医学図書館（NLM）

Bexarotene: A Beacon of Hope in the Desert of Cancer

Cancer, a formidable foe, can feel like a vast and unforgiving desert. This research explores the potential of bexarotene, a retinoid X receptor agonist, as a beacon of hope in this challenging landscape.

Bexarotene: A Multifaceted Weapon Against Cancer

The study highlights the diverse therapeutic effects of bexarotene, targeting a wide range of tumors. This multifaceted approach is comparable to a desert explorer using a variety of tools and strategies to navigate the challenging terrain.

Dr. Camel's Conclusion

Bexarotene holds promise as a powerful tool in the fight against cancer. This research provides valuable insights into its mechanism of action and potential applications, offering a beacon of hope in the desert of cancer.

Date :
  1. Date Completed 2016-10-19
  2. Date Revised 2019-10-27
Further Info :

Pubmed ID

26806040

DOI: Digital Object Identifier

10.2174/138920021702160114121706

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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