Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER.

Author: LoAlbert C, OlsonKayla M, RuizJennifer A, TricheElizabeth W

Paper Details 
Original Abstract of the Article :
Multiple sclerosis (MS) is a degenerative neurological condition that results in impairments in multiple domains including cognition, fatigue, and mood. Dalfampridine-extended release (D-ER) has been approved to improve walking in persons with MS. It is plausible that D-ER could improve cognition, f...See full text at original site
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引用元:
https://doi.org/10.1097/WNF.0000000000000130

データ提供:米国国立医学図書館(NLM)

Dalfampridine-ER and Multiple Sclerosis: A Journey Through the Shifting Sands of Cognition, Mood, and Fatigue

Multiple sclerosis (MS) is a chronic neurological condition that can affect multiple domains, including cognition, fatigue, and mood. Dalfampridine-extended release (D-ER) has been approved to improve walking in individuals with MS. This study examined the effects of D-ER on cognition, depression, mood, and fatigue in a group of MS patients.

The researchers conducted an observational study of MS patients treated with D-ER. They explored the relationship between D-ER use and changes in cognitive processing speed, mood, and fatigue. The study found that D-ER was associated with improvements in cognitive processing speed and mood, particularly in patients who experienced improvements in walking speed. However, the researchers did not observe a significant association between D-ER use and fatigue.

A Path to Improved Cognition and Mood

The study provides evidence that D-ER may have beneficial effects on cognition and mood in some MS patients. This information can be valuable for clinicians managing MS patients and for individuals seeking ways to improve their cognitive function and emotional well-being.

Navigating the Shifting Sands of MS Management

For individuals with MS, managing the condition effectively is a continuous journey. Working closely with your doctor to explore treatment options, including medications like D-ER, and addressing any concerns about cognition, mood, or fatigue is crucial.

Dr. Camel's Conclusion

This study reminds us that the desert of MS can be challenging, but there are oases of hope. D-ER offers a potential path to improving cognition and mood in some MS patients, providing a sense of relief and empowering them to navigate their condition with greater ease.

Date :
  1. Date Completed 2016-12-13
  2. Date Revised 2022-03-11
Further Info :

Pubmed ID

26818040

DOI: Digital Object Identifier

10.1097/WNF.0000000000000130

Related Literature

SNS
PICO Info
in preparation
Languages

English

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