Intermittent BRAF Inhibition Can Achieve Prolonged Disease Control in BRAF Mutant Melanoma.

Author: BryceAlan, JainTania

Paper Details 
Original Abstract of the Article :
BRAF V600E is the most common somatic mutation seen in patients with metastatic melanoma. BRAF inhibitors (BRAFi), along with MEK inhibitors (MEKi), have been shown to improve overall survival in these patients with a median time to resistance of 6-10 months. We describe a patient with an ongoing re...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725676/

データ提供:米国国立医学図書館(NLM)

Intermittent BRAF Inhibition Can Achieve Prolonged Disease Control in BRAF Mutant Melanoma

Imagine melanoma as a treacherous desert, a challenging environment for those who venture there. This research, published in 2016, explores the possibility of using intermittent therapy with BRAF inhibitors, drugs that target a specific mutation in the BRAF gene, to manage BRAF mutant melanoma. This approach aims to control the disease while minimizing the side effects associated with continuous treatment.

Intermittent Therapy - A New Approach to Cancer Treatment

The study describes a patient who achieved a remarkable 48-month response with intermittent BRAF inhibitor therapy. It's like a wise desert traveler, using strategic pauses to conserve energy and resources during a long journey. The researchers suggest that this approach could provide a way to control melanoma for extended periods while reducing the burden of side effects on patients.

Managing Cancer - Balancing Treatment and Quality of Life

This research opens new possibilities for managing melanoma, highlighting the value of personalized medicine and finding the right balance between treatment and quality of life. It's a reminder that, just as a camel must adapt its pace and rest periods to the demands of the desert, we need to find a rhythm that works for each individual in the fight against cancer. This research is a beacon of hope, showing that we can navigate the challenges of cancer with greater control and flexibility.

Dr.Camel's Conclusion

This research offers a fresh perspective on cancer treatment, demonstrating the potential of intermittent therapy to provide lasting disease control while minimizing side effects. It's a testament to the ingenuity of medical research and the ongoing quest to improve the lives of cancer patients. It's a journey of discovery, just like a camel's trek across the vast desert, leading us to new and promising horizons.

Date :
  1. Date Completed 2016-01-29
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

26824010

DOI: Digital Object Identifier

PMC4725676

Related Literature

SNS
PICO Info
in preparation
Languages

English

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