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Aggravation of atonic seizures by rufinamide: A case report.

Author: AydınAli, AydınlıNur, BektaşGonca, Pembegül YıldızEdibe, TatlıBurak, ÇalışkanMine, ÖzmenMeral

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Rufinamide, a novel antiepileptic drug, is used to treat Lennox-Gastaut syndrome and provides seizure control, especially for tonic and atonic seizures. It is expected to be effective in intractable epilepsy when atonic and tonic seizures exist. However, in some patients, rufinamide can worsen seizures.
Paper Details　
Original Abstract of the Article :
Rufinamide is a novel antiepileptic drug used as adjunctive therapy in patients with Lennox-Gastaut syndrome and provides seizure control especially in tonic and atonic seizures. Rufinamide is expected to be effective in intractable epilepsy when atonic and tonic seizures exist. However, rufinamide ...See full text at original site
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引用元：
https://doi.org/10.1016/j.braindev.2016.02.005

データ提供：米国国立医学図書館（NLM）

Rufinamide and Atonic Seizures: A Complicated Landscape

Rufinamide, a medication used to treat epilepsy, can be like a double-edged sword in the fight against seizures. While it is often effective, it can sometimes worsen seizures, presenting a complex challenge for physicians and patients. This research explores the potential for rufinamide to aggravate atonic seizures, a type of seizure characterized by sudden muscle weakness.

Navigating the Terrain of Epilepsy Treatment

This case report highlights the potential for rufinamide to exacerbate atonic seizures in some individuals. It underscores the importance of careful monitoring for seizure frequency and type when prescribing rufinamide, especially in patients with Lennox-Gastaut syndrome. This research emphasizes the need for personalized approaches to epilepsy treatment, carefully considering individual patient needs and potential risks.

A Careful Journey Through the Desert of Seizures

This research reminds us that even with modern medications, the treatment of epilepsy can be a complex journey, full of potential pitfalls. It's like a camel crossing a desert—the traveler must be aware of the terrain and potential hazards to ensure a safe and successful journey.

Dr.Camel's Conclusion

This research reminds us that the treatment of epilepsy can be a challenging journey, like a camel navigating a desert full of hidden dangers. It emphasizes the need for careful monitoring and personalized treatment plans, tailored to the specific needs of each patient.

Date :
  1. Date Completed 2017-01-12
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26906013

DOI: Digital Object Identifier

10.1016/j.braindev.2016.02.005

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・Effects of rufinamide
SNS
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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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