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[Methodology for Estimating the Risk of Adverse Drug Reactions in Pregnant Women: Analysis of the Japanese Adverse Drug Event Report Database].

Author: GotoNobuyuki, MoriChiyo, OhtsuFumiko, SakaiTakamasa, SakataHiroshi, SekiyaYasuaki

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study explored the use of the Japanese Adverse Drug Event Report (JADER) database to identify drug side effects in pregnant women. The study found that analyzing reports specifically on pregnant women in the JADER database was more effective than analyzing all reports in the database.
Paper Details　
Original Abstract of the Article :
Safety information regarding drug use during pregnancy is insufficient. The present study aimed to establish an optimal signal detection method to identify adverse drug reactions in pregnant women and to evaluate information in the Japanese Adverse Drug Event Report (JADER) database between April 20...See full text at original site
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引用元：
https://doi.org/10.1248/yakushi.15-00235

データ提供：米国国立医学図書館（NLM）

Unveiling the Risks of Medications During Pregnancy

This study ventures into the delicate world of drug safety during pregnancy, where navigating the desert of potential risks is a constant challenge. The researchers used data from the Japanese Adverse Drug Event Report (JADER) database to analyze adverse drug reactions in pregnant women.

A New Approach to Signal Detection

The researchers developed a method for identifying potential adverse drug reactions in pregnant women, similar to a camel detecting subtle changes in the desert landscape. This method, based on the proportional reporting ratio (PRR) and reporting odds ratio (ROR), proved effective in identifying risks associated with antithyroid drugs and ritodrine.

Navigating the Risks of Pregnancy

This research provides valuable insights for healthcare professionals and pregnant women alike, emphasizing the importance of careful monitoring and risk assessment when it comes to medication use during pregnancy. It is a crucial step towards ensuring the well-being of both mother and child.

Dr.Camel's Conclusion

This study underscores the importance of careful navigation through the desert of potential risks associated with medication use during pregnancy. The research offers valuable insights for minimizing risks and promoting the safety of both mother and child.

Date :
  1. Date Completed 2017-01-09
  2. Date Revised 2017-01-10
Further Info :

Pubmed ID

26935093

DOI: Digital Object Identifier

10.1248/yakushi.15-00235

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Languages

Japanese

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