cabozantinib (COMETRIQ⁰). In medullary thyroid cancer: more harmful than beneficial, as is vandetanib.

Author:

Paper Details 
Original Abstract of the Article :
Surgery is the mainstay of treatment for medullary thyroid cancer. Cytotoxic chemotherapy is generally ineffective in patients with progressive, inoperable, advanced-stage or metastatic tumours. Vandetanib is also authorised in this setting, but it has more harms than benefits. Cabozantinib, like va...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/26942253

データ提供:米国国立医学図書館(NLM)

Cabozantinib and Vandetanib for Medullary Thyroid Cancer: A Critical Assessment

Medullary thyroid cancer, a rare type of thyroid cancer, presents unique challenges for treatment. This study critically evaluates the use of two targeted therapies, cabozantinib and vandetanib, in the management of this disease. The researchers analyze the benefits and risks associated with these medications based on available clinical data.

Cabozantinib and Vandetanib: Weighing the Risks and Benefits

The study concludes that both cabozantinib and vandetanib have more harms than benefits in the treatment of medullary thyroid cancer. While these medications may show some favorable effects on tumor imaging and certain laboratory parameters, they do not prolong survival or improve symptoms. Furthermore, they are associated with a range of serious side effects, including diarrhea, hand-foot syndrome, hypertension, and bleeding. The study highlights the need for a cautious approach when considering these medications and underscores the importance of tailored symptomatic care.

Medullary Thyroid Cancer: Prioritizing Patient Well-being

This study emphasizes the importance of carefully considering the potential risks and benefits of any treatment, particularly for rare cancers like medullary thyroid cancer. It reinforces the need for individualized approaches to care that prioritize patient well-being and optimize quality of life.

Dr.Camel's Conclusion

Like a camel choosing its path through a rugged desert landscape, we must carefully consider the potential obstacles and rewards of our choices in healthcare. This study serves as a compass, guiding us to prioritize patient well-being and seek treatments that offer the best balance of benefit and risk. In the vast desert of medical research, we must always strive for clarity and prioritize the needs of our patients.

Date :
  1. Date Completed 2016-03-21
  2. Date Revised 2022-03-25
Further Info :

Pubmed ID

26942253

DOI: Digital Object Identifier

26942253

Related Literature

SNS
PICO Info
in preparation
Languages

English

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